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Folate deficiency, also known as vitamin B 9 deficiency, is a low level of folate and derivatives in the body. [1] This may result in megaloblastic anemia in which red blood cells become abnormally large, and folate deficiency anemia is the term given for this medical condition. [3] Signs of folate deficiency are often subtle. [4]
Megaloblastic anemia, the most common cause of macrocytic anemia, is due to a deficiency of either vitamin B 12, folic acid, or both. [81] Deficiency in folate or vitamin B 12 can be due either to inadequate intake or insufficient absorption. Folate deficiency normally does not produce neurological symptoms, while B 12 deficiency does.
Neuropsychiatric symptoms can precede hematological signs and are often the presenting manifestation of B 12 deficiency. [145] Anemia can be prevented or masked by folic acid in which activate tetrahydrofolate (THF) needed for DNA synthesis. [146]
Look for these warning signs of vitamin B12 deficiency. You could be experiencing both mental and physical symptoms. ... Pernicious anemia. ... Vitamin B-12 1,000 mcg with Folic Acid. amazon.com ...
Deficiency can also result from rare genetic factors, such as mutations in the MTHFR gene that lead to compromised folate metabolism. [33] [34] Cerebral folate deficiency is a rare condition in which concentrations of folate are low in the brain despite being normal in the blood. [35] Vitamin B 12 deficiency: Anemia, neurological and digestive ...
Folic acid is a synthetic form of folate, a B vitamin found naturally in many foods. ... Iron deficiency anemia can cause a range of symptoms, including dizziness, heart palpitations and physical ...
In fact, a severe deficiency in folate can result in a condition called folate-deficiency anemia, which has symptoms like hair thinning and pigmentation changes in the hair.
Nutritional anemia can be caused by a lack of iron, protein, vitamin B12, and other vitamins and minerals that are needed for the formation of hemoglobin. However, Iron deficiency anemia is the most common nutritional disorder. [7] Signs of anemia include cyanosis, jaundice, and easy bruising. [7]