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In the pharmaceutical industry, drug dissolution testing is routinely used to provide critical in vitro drug release information for both quality control purposes, i.e., to assess batch-to-batch consistency of solid oral dosage forms such as tablets, and drug development, i.e., to predict in vivo drug release profiles. [1]
Tablet hardness testing is a laboratory technique used by the pharmaceutical industry to determine the breaking point and structural integrity of a tablet and find out how it changes "under conditions of storage, transportation, packaging and handling before usage" [1] The breaking point of a tablet is based on its shape. [2]
A soil test is a laboratory or in-situ analysis to determine the chemical, physical or biological characteristics of a soil. Possibly the most widely conducted soil tests are those performed to estimate the plant-available concentrations of nutrients in order to provide fertilizer recommendations in agriculture.
In pharmaceutics, sink condition is a term mostly related to the dissolution testing procedure.. It means using a sheer volume of solvent, usually about 5 to 10 times greater than the volume present in the saturated solution of the targeted chemical (often the API, and sometimes the excipients) contained in the dosage form being tested.
Friability and abrasion testing is performed in rotating testing drums, designed according to the pharmacopeia. The measured parameter is weight loss before and after testing and tumbling the tablets at a particular time and speed. In the friability test drum tablets are being carried up by a "shovel" and dropped.
The activity of soil is the ratio of the plasticity index to the clay size fraction. If activity is less than 0.75, the soil is inactive. If activity exceeds 1.4, then the soil is termed active. If activity lies within the above values, then the soil will be moderately active. [10]
The cone penetration or cone penetrometer test (CPT) is a method used to determine the geotechnical engineering properties of soils and delineating soil stratigraphy. It was initially developed in the 1950s at the Dutch Laboratory for Soil Mechanics in Delft to investigate soft soils. Based on this history it has also been called the "Dutch ...
A percolation test (colloquially called a perc test) is a test to determine the water absorption rate of soil (that is, its capacity for percolation) in preparation for the building of a septic drain field (leach field) or infiltration basin. [1] The results of a percolation test are required to design a septic system properly.