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Experiments with pharmacological agents that cause depletion of monoamines have shown that this depletion does not cause depression in healthy people. [56] [57] Another problem that presents is that drugs that deplete monoamines may actually have antidepressants properties.
Use of antidepressants during pregnancy may result in fetus abnormalities affecting functional development of the brain and behavior. [90] Studies have shown correlations between pregnant women treated with SNRIs and risk of hypertensive disorders, [ 91 ] preeclampsia, [ 92 ] miscarriage, [ 93 ] seizures in children, [ 94 ] and many other ...
The results highlight the importance of discussing antidepressant side effects and medication adherence with individuals taking these medications. Comparing 8 antidepressants’ effects on weight
Desvenlafaxine is a synthetic form of the isolated major active metabolite of venlafaxine, and is categorized as a serotonin-norepinephrine reuptake inhibitor (SNRI). When most normal metabolizers take venlafaxine, approximately 70% of the dose is metabolized into desvenlafaxine, so the effects of the two drugs are expected to be very similar. [18]
The pharmacology of antidepressants is not entirely clear.. The earliest and probably most widely accepted scientific theory of antidepressant action is the monoamine hypothesis (which can be traced back to the 1950s), which states that depression is due to an imbalance (most often a deficiency) of the monoamine neurotransmitters (namely serotonin, norepinephrine and dopamine). [1]
A new Canadian study suggests that women who take antidepressants during pregnancy may be more likely to give birth to children with autism. Skip to main content. 24/7 Help. For premium support ...
Vitamin B12 deficiency symptoms . Vitamin B12 deficiency has a few hallmark symptoms, according to doctors: Lack of energy. Mental fatigue. Nausea, vomiting, or diarrhea. Lack of appetite. Weight loss
Phenelzine has also been linked to vitamin B 6 deficiency. [22] Transaminases such as GABA-transaminase have been shown to be dependent upon vitamin B 6 [ 23 ] and may be involved in a potentially related process, since the phenelzine metabolite phenylethylidenehydrazine (PEH) is a GABA-transaminase inhibitor.