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Experiments with pharmacological agents that cause depletion of monoamines have shown that this depletion does not cause depression in healthy people. [ 56 ] [ 57 ] Another problem that presents is that drugs that deplete monoamines may actually have antidepressants properties.
Nortriptyline may cause problems if taken during pregnancy. [8] Use during breastfeeding appears to be relatively safe. [7] It is a tricyclic antidepressant (TCA) and is believed to work by altering levels of serotonin and norepinephrine. [8] Nortriptyline was approved for medical use in the United States in 1964. [8]
Otherwise, causes may include increased needs as with pregnancy, and in those with shortened red blood cell lifespan. [1] Folate deficiency can be secondary to vitamin B 12 deficiency or a defect in homocysteine methyl transferase that leads to a "folate trap" in which is an inactive metabolite that cannot be recovered. [1]
Lithium is teratogenic and can cause birth defects at high doses, especially during the first trimester of pregnancy. The use of lithium while breastfeeding is controversial; however, many international health authorities advise against it, and the long-term outcomes of perinatal lithium exposure have not been studied. [ 6 ]
A new Canadian study suggests that women who take antidepressants during pregnancy may be more likely to give birth to children with autism. Skip to main content. 24/7 Help. For premium support ...
“The most common uses of antidepressants are for depression and anxiety, where they can significantly boost mood, energy while reducing negative thoughts, obsessive thoughts, and rumination.
This complication can cause nutritional deficiency, low pregnancy weight gain, dehydration, and vitamin, electrolyte, and acid-based disturbances in the mother. It has been shown to cause low birth weight, small gestational age, preterm birth, and poor APGAR scores in the infant.
Vitamin B12 supplements might be better for folks with metabolic syndrome or those who have a deficiency. More research is needed to know if vitamin B12 is an effective weight loss aid.