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Colin Albert Murdoch ONZM (6 February 1929 – 4 May 2008) was a New Zealand pharmacist and veterinarian who made a number of significant inventions, in particular the tranquilliser gun, the disposable hypodermic syringe and the child-proof medicine container. He had a total of 46 patents registered in his name.
Advertisement for Thorazine (chlorpromazine) from the 1950s, reflecting the perceptions of psychosis, including the now-discredited perception of a tendency towards violence, from the time when antipsychotics were discovered [30] The original antipsychotic drugs were happened upon largely by chance and then tested for their effectiveness.
In 1907 Alfred Bertheim synthesized Arsphenamine, the first man-made antibiotic. In 1927 Erik Rotheim patented the first aerosol spray can. In 1933 Robert Pauli Scherer created a method to develop softgels. William Roberts studies about penicillin were continued by Alexander Fleming, who in 1928 concluded that penicillin had an antibiotic ...
The first recorded use of the term tranquilizer dates from the early nineteenth century. [275] In 1953 Frederik F. Yonkman, a chemist at the Swiss-based Cibapharmaceutical company, first used the term tranquilizer to differentiate reserpine from the older sedatives. [276]
In the mid-1970s, "flying dart" for 12 gauge shotguns and experimental cartridges for immobilization of wild animals for the SPSh-44 pistol were made and tested. [9] In the second half of the 1980s, the standard tranquillizer gun in the USSR was a single-shot IZh-18M shotgun (a dart with a dose of sedative was fired with a blank cartridge). [10]
Meprobamate—marketed as Miltown by Wallace Laboratories and Equanil by Wyeth, among others—is a carbamate derivative used as an anxiolytic drug. It was the best-selling minor tranquilizer for a time, but has largely been replaced by the benzodiazepines due to their wider therapeutic index (lower risk of toxicity at therapeutically prescribed doses) and lower incidence of serious side effects.
This made China become the world's first print culture. [ 299 ] Late 3rd century – Early 4th century: Water turbine in the Roman Empire in modern-day Tunisia .
The Royal College of Apothecaries of the City and Kingdom of Valencia was founded in 1441, considered the oldest in the world, with full administrative and legislative powers. The apothecaries of Valencia were the first in the world to elaborate their medicines, with the same criteria that are currently required in the official pharmacopoeias. [18]