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In 1858 Dr. M. Sales Giron invented the first pressurized inhaler. Amphetamine was first synthesized in 1887 in Germany by Romanian chemist Lazăr Edeleanu who named it phenylisopropylamine ; [ 23 ] [ 24 ] [ 25 ] its stimulant effects remained unknown until 1927, when it was independently resynthesized by Gordon Alles and reported to have ...
The first recorded use of the term tranquilizer dates from the early nineteenth century. [282] In 1953 Frederik F. Yonkman, a chemist at the Swiss-based Cibapharmaceutical company, first used the term tranquilizer to differentiate reserpine from the older sedatives. [283]
The timeline of historic inventions is a chronological list of particularly significant technological inventions and their inventors, where known. [ a ] The dates in this article make frequent use of the units mya and kya , which refer to millions and thousands of years ago, respectively.
These timelines of world history detail recorded events since the creation of writing roughly 5000 years ago to the present day. For events from c. 3200 BC – c. 500 see: Timeline of ancient history; For events from c. 500 – c. 1499, see: Timeline of post-classical history; For events from c. 1500, see: Timelines of modern history
500 BC – Pills were used. They were presumably invented so that measured amounts of a medicinal substance could be delivered to a patient. 510–430 BC – Alcmaeon of Croton scientific anatomic dissections. He studied the optic nerves and the brain, arguing that the brain was the seat of the senses and intelligence.
Advertisement for Thorazine (chlorpromazine) from the 1950s, reflecting the perceptions of psychosis, including the now-discredited perception of a tendency towards violence, from the time when antipsychotics were discovered [30] The original antipsychotic drugs were happened upon largely by chance and then tested for their effectiveness.
Colin Albert Murdoch ONZM (6 February 1929 – 4 May 2008) was a New Zealand pharmacist and veterinarian who made a number of significant inventions, in particular the tranquilliser gun, the disposable hypodermic syringe and the child-proof medicine container.
The World Psychiatric Association was founded. 1952. The first published clinical trial of chlorpromazine which is the first antipsychotic (invented by Henri Laborit, Jean Delay and Pierre Deniker) was conducted at Sainte-Anne Hospital Center in Paris. Known as Largactil in Europe, it was brought to Montreal by Heinz Lehman and named Thorazine.