Search results
Results from the WOW.Com Content Network
An agouti dog, also called wolf sable. In dogs, the agouti gene is associated with various coat colors and patterns. [10]The alleles at the A locus are related to the production of agouti-signaling protein (ASIP) and determine whether an animal expresses an agouti appearance and, by controlling the distribution of pigment in individual hairs, what type of agouti.
Agouti-signaling protein is a protein that in humans is encoded by the ASIP gene. [5] [6] It is responsible for the distribution of melanin pigment in mammals.[7] [8] Agouti interacts with the melanocortin 1 receptor to determine whether the melanocyte (pigment cell) produces phaeomelanin (a red to yellow pigment), or eumelanin (a brown to black pigment). [9]
17202 Ensembl ENSG00000166603 ENSMUSG00000047259 UniProt P32245 P56450 RefSeq (mRNA) NM_005912 NM_016977 RefSeq (protein) NP_005903 NP_058673 Location (UCSC) Chr 18: 60.37 – 60.37 Mb Chr 18: 66.99 – 66.99 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Melanocortin 4 receptor (MC 4 R) is a melanocortin receptor that in humans is encoded by the MC4R gene. It encodes the MC 4 R ...
The agouti gene in mice is largely responsible for determining coat colour. The wild-type allele produces a blend of yellow and black pigmentation in each hair of the mouse. This yellow and black blend may be referred to as 'agouti' in colour. [3] One of the mutant alleles of the agouti gene
In a mice model, the mice fed on a BPA diet were more likely to have a yellow coat corresponding to their lower methylation state in the promoter regions of the retrotransposon upstream of the Agouti gene. The Agouti gene is responsible for determining whether an animal's coat will be banded (agouti) or solid (non-agouti).
This system is a principal nexus of body weight regulation through its role in appetite and energy expenditure via leptin, ghrelin and agouti-related protein. [ 3 ] [ 4 ] It receives inputs from hormones , nutrients and afferent neural inputs, and is unique in its composition of fibers which express both agonists and antagonists of melanocortin ...
An animal testing laboratory at Elon Musk's Neuralink brain technology company was found to have "objectionable conditions or practices" by the Food and Drug Administration, which cited the ...
11604 Ensembl ENSG00000159723 ENSMUSG00000005705 UniProt O00253 P56473 RefSeq (mRNA) NM_001138 NM_001271806 NM_007427 RefSeq (protein) NP_001129 NP_001258735 NP_031453 Location (UCSC) Chr 16: 67.48 – 67.48 Mb Chr 8: 106.29 – 106.36 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the ...