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Crigler–Najjar syndrome is a rare inherited disorder affecting the metabolism of bilirubin, a chemical formed from the breakdown of the heme in red blood cells. The disorder results in a form of nonhemolytic jaundice, which results in high levels of unconjugated bilirubin and often leads to brain damage in infants.
Whereas breastfeeding jaundice is a mechanical problem, breast milk jaundice is a biochemical occurrence and the higher bilirubin possibly acts as an antioxidant. Breast milk jaundice occurs later in the newborn period, with the bilirubin level usually peaking in the sixth to 14th days of life.
774 Other perinatal jaundice. 774.2 Jaundice, newborn, prematurity; 774.3 Jaundice, newborn, unspec. 774.3 Lucey-Driscoll syndrome. 774.39 Jaundice, newborn, breast milk; 775 Endocrine and metabolic disturbances specific to the fetus and newborn. 775.0 Infant of diabetic mother syndrome; 775.4 Hypocalcemia; 775.6 Hypoglycemia, neonatal
Jaundice is commonly associated with severity of disease with an incidence of up to 40% of patients requiring intensive care in ICU experiencing jaundice. [48] The causes of jaundice in the intensive care setting is both due to jaundice as the primary reason for ICU stay or as a morbidity to an underlying disease (i.e. sepsis). [48]
Breast milk is proven to be chemically different for each mother and infant pair. For example, a premature infant's mother will have different milk than a mature infant's mother. Breast milk can also change if an infection is detected in the infant. [2] This natural prevention is tailored toward each infant.
The common cause is congenital, but it can also be caused by maternal steroids passed on through breast milk to the newborn. It is different from breast feeding-associated jaundice (breast-fed infants have higher bilirubin levels than formula-fed ones).
Two people are dead after a plane crashed into a building near the Daniel K. Inouye International Airport in Honolulu, according to reports. At around 3:15 p.m. local time on Tuesday, Kamaka Air ...
[1] [2] Medications, when administered to breastfeeding mothers, almost always are transferred to breast milk, albeit usually in small quantities. [3] The degree of impact on the nursing infant varies, with many medications posing minimal risk. Nonetheless, informed decision-making and professional guidance is needed.