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Crigler–Najjar syndrome is a rare inherited disorder affecting the metabolism of bilirubin, a chemical formed from the breakdown of the heme in red blood cells. The disorder results in a form of nonhemolytic jaundice, which results in high levels of unconjugated bilirubin and often leads to brain damage in infants.
Whereas breastfeeding jaundice is a mechanical problem, breast milk jaundice is a biochemical occurrence and the higher bilirubin possibly acts as an antioxidant. Breast milk jaundice occurs later in the newborn period, with the bilirubin level usually peaking in the sixth to 14th days of life.
The anti-inflammatory components in breast milk are those bioactive substances that confer or increase the anti-inflammatory response in a breastfeeding infant. [ 1 ] Anti-inflammatory Components of Breastmilk
Breast milk is proven to be chemically different for each mother and infant pair. For example, a premature infant's mother will have different milk than a mature infant's mother. Breast milk can also change if an infection is detected in the infant. [2] This natural prevention is tailored toward each infant.
Jaundice is commonly associated with severity of disease with an incidence of up to 40% of patients requiring intensive care in ICU experiencing jaundice. [48] The causes of jaundice in the intensive care setting is both due to jaundice as the primary reason for ICU stay or as a morbidity to an underlying disease (i.e. sepsis). [48]
The causes of breast milk jaundice include variations in bilirubin metabolism, genetic variations, and variations in breastmilk, including the harmless and helpful germs found naturally on the surface of the skin and in the breastmilk. [40] Breast milk jaundice is usually not a reason to stop nursing. [119]
A few short bursts of exercise throughout the day may reduce heart disease risk by 50%, according to new research. Women specifically showed the most pronounced effects of short bursts of activity ...
The prophylactic antibiotic use of human milk may be important in areas where mothers and infants do not have easy access to medicine, such as people living in developing countries. [24] Under these circumstances, practice of HBM therapy as medicine will be a determining factor in infant recovery and survival.