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The tissue is skin from a patient with Pemphigus vulgaris. Note the intercellular IgG deposits in the epidermis and the early intraepidermal vesicle caused by acantholysis. Pemphigus (/ ˈ p ɛ m f ɪ ɡ ə s / or / p ɛ m ˈ f aɪ ɡ ə s /) is a rare group of blistering autoimmune diseases that affect the skin and mucous membranes. [1]
Pemphigus is a genus of true bugs belonging to the family Aphididae. [1] The genus has almost cosmopolitan distribution. [1] Species: [1] Pemphigus andropogiae Shinji ...
Pemphigus vulgaris is a rare chronic blistering skin disease and the most common form of pemphigus.Pemphigus was derived from the Greek word pemphix, meaning blister. [1] It is classified as a type II hypersensitivity reaction in which antibodies are formed against desmosomes, components of the skin that function to keep certain layers of skin bound to each other.
Drug-induced pemphigus: IgG: Desmoglein 3 Desmoglein 1: 130 160 Subcorneal pustular dermatosis type of IgA pemphigus: IgA1: Desmocollin 1: 110/100 Intraepidermal neutrophilic type of IgA pemphigus: IgA1: Unknown: Pemphigus erythematosus (Senear–Usher syndrome) [nb 3] IgG: Desmoglein 1: 160 Fogo selvagem: IgG: Desmoglein 1: 160 Pemphigus ...
Pemphigus foliaceus is diagnosed base on history, biopsy of the affected skin, and testing either a blood sample or a skin sample for the antibodies that cause pemphigus. [ citation needed ] The differential diagnosis includes other forms of pemphigus, bullous impetigo , subcorneal pustular dermatosis, subacute cutaneous LE , and seborrheic ...
Pemphigus erythematosus (Senear-Usher Syndrome) is a rare form of pemphigus with features of pemphigus foliaceus and lupus erythematosus. [ 1 ] [ 2 ] It was first described by Francis Senear and Barney Usher at the University of Illinois College of Medicine in 1926. [ 3 ]
Paraneoplastic pemphigus (PNP) is an autoimmune disorder stemming from an underlying tumor. It is hypothesized that antigens associated with the tumor trigger an immune response resulting in blistering of the skin and mucous membranes .
IgA pemphigus is a subtype of pemphigus with two distinct forms: . Subcorneal pustular dermatosis (also known as Sneddon–Wilkinson disease and pustulosis subcornealis) [1] is skin condition that is a rare, chronic, recurrent, pustular eruption characterized histopathologically by subcorneal pustules that contain abundant neutrophils.