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Sirtris Pharmaceuticals, Inc. was a biotechnology company based in Cambridge, MA that developed therapies for type 2 diabetes, cancer, and other diseases. Conceived in 2004 by Harvard University biologist David Sinclair and Andrew Perlman, [1] and founded that year by Sinclair and Perlman, along with Christoph Westphal, Richard Aldrich, Richard Pops, and Paul Schimmel, [2] the company was ...
[53] [58] [59] [60] In 2004, Harvard University professor David Sinclair co-founded Sirtris Pharmaceuticals, the initial product of which was a resveratrol formulation. [ 61 ] [ 62 ] [ 63 ] Sirtris was purchased and made a subsidiary of GlaxoSmithKline in 2008 for $720 million and shut down in 2013, without successful drug development.
David Andrew Sinclair AO (born June 26, 1969) is an Australian-American biologist and academic known for his research on aging and epigenetics. Sinclair is a professor of genetics at Harvard Medical School and the founding director of the Paul F. Glenn Laboratories for the Biological Mechanisms of Aging at Harvard.
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At times, he’ll post nudes, his bulging musculature courtesy of 800-pound leg presses, a strict diet (mostly vegan, no wine—too many calories), and some 100 supplements a day.
Dr. Zalan Alam, a primary care physician, takes supplements every day. He takes supplements including zinc and lion's mane. Alam said choosing which supplements to take is "all about personalization."
A review for Boston Magazine called Sinclair "one of science's most controversial figures" and said many in the scientific community were skeptical of claims he made about human longevity. University of Alabama biology professor Steven N. Austad said, "David is a good friend, but I do think he's been guilty of making excessive claims."
A doctor who's 78 but says he has a biological age of 57.6 shared five of the supplements he takes daily. As life expectancy has grown — the average American is expected to live until 77.5, ...