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Their function is to circulate through the body and initiate a stronger, more rapid antibody response (known as the anamnestic secondary antibody response) if they detect the antigen that had activated their parent B cell (memory B cells and their parent B cells share the same BCR, thus they detect the same antigen). [26]
T cells are grouped into a series of subsets based on their function. CD4 and CD8 T cells are selected in the thymus, but undergo further differentiation in the periphery to specialized cells which have different functions. T cell subsets were initially defined by function, but also have associated gene or protein expression patterns.
A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. [1] Lymphocytes include T cells (for cell-mediated and cytotoxic adaptive immunity), B cells (for humoral, antibody-driven adaptive immunity), [2] [3] and innate lymphoid cells (ILCs; "innate T cell-like" cells involved in mucosal immunity and homeostasis), of which natural killer cells are an ...
The mucosa-associated lymphoid tissue (MALT), also called mucosa-associated lymphatic tissue, is a diffuse system of small concentrations of lymphoid tissue found in various submucosal membrane sites of the body, such as the gastrointestinal tract, nasopharynx, thyroid, breast, lung, salivary glands, eye, and skin.
The T cell-dependent processes are subdivided into primary and secondary responses: a primary response (meaning that the T cell is present at the time of initial contact by the B cell with the antigen) produces short-lived cells that remain in the extramedullary regions of lymph nodes; a secondary response produces longer-lived cells that ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 11 December 2024. List of organ systems in the human body Part of a series of lists about Human anatomy General Features Regions Variations Movements Systems Structures Arteries Bones Eponymous Foramina Glands endocrine exocrine Lymphatic vessels Nerves Organs Systems Veins Muscles Abductors Adductors ...
However, T and B lymphocytes are very distinct cell lineages and they ‘grow up’ in different places in the body. They perform quite different (although co-operative) functions in the body. No evidence has ever been found that T and B cells can ever interconvert. T and B cells are biochemically distinct and this is reflected in the differing ...
Once mature, T cells emigrate from the thymus to provide vital functions in the immune system. [11] [12] Each T cell has a distinct T cell receptor, suited to a specific substance, called an antigen. [12] Most T cell receptors bind to the major histocompatibility complex on cells of the body.