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Carpaine in papaya leaves extract is the major active compounds that contributes to the anti-thrombocytopenic activity (raising the platelet counts in patient's blood). For example, a treatment used for a 45-year-old male patient in Pakistan diagonosed with dengue fever involved administering 25mL of the extracted Carpaine twice daily for five ...
Papaya Plant and fruit, from Koehler's Medicinal-Plants (1887) Conservation status Data Deficient (IUCN 3.1) Scientific classification Kingdom: Plantae Clade: Tracheophytes Clade: Angiosperms Clade: Eudicots Clade: Rosids Order: Brassicales Family: Caricaceae Genus: Carica Species: C. papaya Binomial name Carica papaya L. The papaya, papaw, is the plant species Carica papaya, one of the 21 ...
In China, both the tree and its fruit are called mùguā (木瓜), which also refers to papaya and the flowering quince (Chaenomeles speciosa). In Korea the tree is called mogwa-namu ( 모과나무 ) and the fruit mogwa ( 모과 ; from mokgwa ( Korean : 목과 ; Hanja : 木瓜 ), the Korean reading of the Chinese characters).
The name pawpaw or papaw, first recorded in print in English in 1598, originally meant the giant herb Carica papaya or its fruit (as it still commonly does in many English-speaking communities, including Australia, New Zealand, and South Africa). Daniel F. Austin's Florida Ethnobotany [18] states that: The original "papaw" ... is Carica papaya ...
Platelets are regulators of hemostasis and thrombosis. Platelets become active in the blood following vascular injury. Vascular injury causes platelets to stick to the cellular matrix that is exposed under the endothelium, form a platelet plug, and then form a thrombus. Platelets are essential in the formation of an occlusive thrombus and are ...
Some species, such as the papaya, bear edible fruit and produce papain. [3] Based on molecular analyses, this family has been proposed to have originated in Africa in the early Cenozoic era, ~66 million years ago (mya). The dispersal from Africa to Central America occurred ~35 mya, possibly via ocean currents from the Congo delta.
The change in the recipient's platelet count after transfusion is termed the "increment" and is calculated by subtracting the pre-transfusion platelet count from the post-transfusion count. Many factors affect the increment including body size, the number of platelets transfused, and clinical features that may cause premature destruction of the ...
Upon reperfusion of the ischemic myocardium, there is development of calcium overload or excess in the heart cell (cardiomyocytes). This increase in calcium leads to activation of calpain. [19] [irrelevant citation] Recently calpain has been implicated in promoting high altitude induced venous thrombosis by mediating platelet hyperactivation. [10]