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Clarithromycin, sold under the brand name Biaxin among others, is an antibiotic used to treat various bacterial infections. [3] This includes strep throat, pneumonia, skin infections, H. pylori infection, and Lyme disease, among others. [3] Clarithromycin can be taken by mouth as a tablet or liquid or can be infused intravenously. [3]
Patient's appearance of the jaundice side effect. Clarithromycin may cause gastrointestinal adverse effects including vomiting, nausea, taste alteration and abdominal pain. [39] This medication can also cause liver toxicity. [39] Symptoms of liver damage include anorexia, dark urine, jaundice, tender abdomen and pruritus. [39]
Common side effects include an upset stomach. [6] Other side effects may include muscle or joint pains, shortness of breath, and liver problems. [6] [8] It appears to be safe during pregnancy and breastfeeding. [6] It should not be used in those who are allergic to penicillin. [6] It is a narrow-spectrum beta-lactam antibiotic of the penicillin ...
Helicobacter pylori colonizes the stomach for decades in most people, and induces chronic gastritis, a long-lasting inflammation of the stomach. In most cases symptoms are never experienced but about 10–20% of those infected will ultimately develop gastric and duodenal ulcers, and have a possible 1–2% lifetime risk of gastric cancer.
Tetracyclines are generally used in the treatment of infections of the urinary tract, respiratory tract, and the intestines and are also used in the treatment of chlamydia, especially in patients allergic to β-lactams and macrolides; however, their use for these indications is less popular than it once was due to widespread development of resistance in the causative organisms.
AUC it is a measure of the drug exposure in the body over time. By inhibiting CYP3A4, macrolide antibitiotics, such as erythromycin and clarithromycin, but not azithromycin, can significantly increase the AUC of the drugs that depend on it for clearance, which can lead to higher risk of adverse effects or drug-drug interactions. Azithromycin ...
Azithromycin is an acid-stable antibiotic, so it can be taken orally with no need of protection from gastric acids. It is readily absorbed, but absorption is greater on an empty stomach. Time to peak concentration (T max) in adults is 2.1 to 3.2 hours for oral dosage forms.
Most common side-effects are gastrointestinal, including diarrhea, nausea, abdominal pain and vomiting. Headache and disturbances in taste also occur. Less common side-effects include palpitations, blurred vision, and rashes. Prolonged QTc intervals may also be caused by telithromycin. [3]