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Tooth development begins at week 6 in utero, in the oral epithelium. The process is divided into three stages: Initiation; Morphogenesis and; Histogenesis [2]; At the end of week 7 i.u., localised proliferations of cells in the dental laminae form round and oval swellings known as tooth buds, which will eventually develop into mesenchymal cells and surround the enamel organ.
The tooth bud (sometimes called the tooth germ) is an aggregation of cells that eventually forms a tooth and is organized into three parts: the enamel organ, the dental papilla and the dental follicle. [3] The enamel organ is composed of the outer enamel epithelium, inner enamel epithelium, stellate reticulum and stratum intermedium. [3]
It is organized into three parts: the enamel organ, the dental papilla and the dental follicle. [27] The enamel organ is composed of the outer enamel epithelium, inner enamel epithelium, stellate reticulum and stratum intermedium. [27] These cells give rise to ameloblasts, which produce enamel and the reduced enamel epithelium.
This marks the first appearance of enamel in the body. Ameloblasts make enamel at the location of where the cusps of the teeth are located. Enamel grows outwards, away from the center of the tooth. [citation needed] In the maturation stage, the ameloblasts transport some of the substances used in enamel formation out of the enamel.
Consequently, enamel, unlike many other tissues of the body, has no way to regenerate itself. [17] After destruction of enamel from decay or injury, neither the body nor a dentist can restore the enamel tissue. Enamel can be affected further by non-pathologic processes. Enamel is covered by various structures in relation to the development of ...
The enamel niche is a structure that appears in a histologic slide of a developing tooth from sectioning the slide in a single plane. The enamel organ looks to be connected to the oral epithelium by two or more strands of dental lamina. The enamel niche is the name of the mesenchymal cells which look to be surrounded by the strands of the ...
After the formation of enamel matrix, mineralisation of enamel takes place which is known as maturation. During this stage, the ameloblasts are slightly reduced in length. The stratum intermedium cells lose their cuboidal shape and assumed to be as spindle shape. During this stage, ameloblasts also exhibit microvilli at their distal extremities.
The outer enamel epithelium, also known as the external enamel epithelium, is a layer of cuboidal cells located on the periphery of the enamel organ in a developing tooth. This layer is first seen during the bell stage. The rim of the enamel organ, where the outer and inner enamel epithelium join is called the cervical loop.