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Besides being painful, a nocturnal leg cramp can cause much distress and anxiety. [14] The precise cause of these cramps is unclear. Potential contributing factors include dehydration , low levels of certain minerals ( magnesium , potassium , calcium , and sodium , although the evidence has been mixed), [ 15 ] [ 16 ] [ 17 ] and reduced blood ...
For instance, a study showed how COVID-19 may cause microvascular brain pathology and endothelial cell-death, disrupting the blood–brain barrier. [ 51 ] [ 52 ] Another study identified neuroinflammation and an activation of adaptive and innate immune cells in the brain stem of COVID-19 patients. [ 53 ]
The causes of leg cramps at night can range from nutrient deficiency to tough workouts. Here, experts break down how to prevent and get rid of leg cramps.
Longer-term effects of COVID-19 have become a prevalent aspect of the disease itself. These symptoms can be referred to by many names including post-COVID-19 syndrome, long COVID, and long haulers syndrome. An overall definition of post-COVID conditions (PCC) can be described as a range of symptoms that can last for weeks or months. [83]
Charley horses have many possible causes directly resulting from high or low pH or substrate concentrations in the blood, including hormonal imbalances, dehydration, low levels of magnesium, potassium, or calcium (evidence has been mixed), [5] [6] [7] side effects of medication, or, more seriously, diseases such as amyotrophic lateral sclerosis and neuropathy. [8]
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Typical early symptoms are "tingling" (sort of electrified vibration or paresthesia) or numbness in the extremities, frequent (night) leg cramps, loss of reflexes (in knees), muscle fasciculations, "vibration" feelings, loss of balance, general muscle cramping and nerve pain.
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