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Addiction is a serious risk with heavy recreational amphetamine use, but is unlikely to occur from long-term medical use at therapeutic doses. Very high doses can result in psychosis (e.g., hallucinations , delusions and paranoia ) which rarely occurs at therapeutic doses even during long-term use.
Stimulant use disorder is a type of substance use disorder where the use of stimulants caused clinically significant impairment or distress. It is defined in the DSM-5 as "the continued use of amphetamine-type substances, cocaine, or other stimulants leading to clinically significant impairment or distress, from mild to severe". [1]
After its discovery, amphetamine was purified and put into medical use in the 1900s. [5] Amphetamine was originally sold as a decongestant inhaler in the United States in 1933 and led to widespread ATS abuse in military forces and civilians later on. [5] The details of history of amphetamine can be found here.
DOB is one of the most potent compounds in PiHKAL; while the active dose is similar to that of DOI, another psychedelic amphetamine, DOB has been shown to have a higher efficacy in triggering downstream effects mediated by 5-HT2 receptors, [7] making it likely to be slightly more dangerous than DOI in overdose, due to greater vasoconstrictive ...
The prescription medicine Adderall (dextroamphetamine sulfate/amphetamine sulfate/dextroamphetamine saccharate/amphetamine aspartate monohydrate) is also frequently used recreationally. However, using non-prescribed drugs, using non-prescribed dose regimen, can cause polysubstance dependence , or combined drug intoxication which may lead to ...
Amphetamine is a potent central nervous system (CNS) stimulant of the phenethylamine class that is approved for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. [82] Amphetamine is also used off-label as a performance and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant.
Matt Damon’s Best Screenplay win at the 1998 Academy Awards was a bittersweet moment for the actor’s ex, Minnie Driver. “My face ” Driver, 53, commented on an Instagram clip of Damon, 53 ...
3,4-Methylenedioxyamphetamine (MDA) is an empathogen-entactogen, stimulant, and psychedelic drug of the amphetamine family that is encountered mainly as a recreational drug. [3] In its pharmacology , MDA is a serotonin–norepinephrine–dopamine releasing agent (SNDRA).