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The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
Menstrual Cycle including Menstrual phase (often referred to as "period") A menstrual disorder is characterized as any abnormal condition with regards to a woman's menstrual cycle . There are many different types of menstrual disorders that vary with signs and symptoms, including pain during menstruation, heavy bleeding, or absence of menstruation.
In particular, prostaglandins induce abdominal contractions that can cause pain and gastrointestinal symptoms. [8] [9] The use of certain types of birth control pills can prevent the symptoms of dysmenorrhea because they stop ovulation from occurring. Dysmenorrhea is associated with increased pain sensitivity and heavy menstrual bleeding. [10] [11]
Patients with menstrual Oestrogen-related migraine, but without aura and additional risk factors to stroke, can be benefited from combined oral contraceptives. [83] [84] However, older women and those with a strong family history of problematic headaches may find that using hormonal oral contraceptives worsens their headache. [83] [84]
The most common side-effects of combined hormonal contraceptives include headache, nausea, breast tenderness, and breakthrough bleeding. Vaginal ring use can include additional side-effects including vaginal irritation and vaginal discharge. Contraceptive skin patch use can also include a side-effect of skin irritation around the patch site. [39]
Even women who do not experience intense symptoms or are asymptomatic can become infertile. [41] This can be caused by the formation of scar tissue due to one or more episodes of PID, and can lead to tubal blockage. Both of these increase the risk of the inability to get pregnant, [27] and 1% results in an ectopic pregnancy. [40]
Polymenorrhea, also known as frequent periods, frequent menstruation, or frequent menstrual bleeding, is a menstrual disorder in which menstrual cycles are shorter than 21 days in length and hence where menstruation occurs more frequently than usual. [1] [2] [3] Cycles are regular and menstrual flow is normal in the condition. [3]
However, excessive exercise can cause FHA in normal weight patients who present no abnormal metabolic or gonadotropic laboratory results. In these cases, combined hormonal contraceptive pills will not address the primary cause of menstrual cessation: inhibition of the HPO axis due to excessive exercise. Thus, behavioral modifications should be ...