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Gout is a common form of inflammatory arthritis. It happens due to high levels of uric acid in the body. Researchers estimate that gout impacts one to four percent of people around the world.
Gout (/ ɡ aʊ t / GOWT [7]) is a form of inflammatory arthritis characterized by recurrent attacks of pain in a red, tender, hot, and swollen joint, [2] [8] caused by the deposition of needle-like crystals of uric acid known as monosodium urate crystals. [9] Pain typically comes on rapidly, reaching maximal intensity in less than 12 hours. [5]
When symptomatic, the disease classically begins with symptoms that are similar to a gout attack (thus the moniker pseudogout). These include: [citation needed] severe pain; warmth; swelling of one or more joints; severe fatigue; fever; feeling of malaise or flu-like symptoms; inability to walk or perform everyday tasks or hobbies
Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [4] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...
Uric acid forms when the body breaks down purines, a chemical compound that cells use to form DNA and RNA. Meat and meat products contain purines. ... In fact, men are three to 10 times more ...
Tophi form in the joints, cartilage, bones, and other places throughout the body. Sometimes, tophi break through the skin and appear as white or yellowish-white, chalky nodules. Without treatment, tophi may develop on average about ten years after the onset of gout, although their first appearance can range from three to forty-two years.
A diet rich in sucrose may lead to gout as it raises the level of insulin, which prevents excretion of uric acid from the body. As the concentration of uric acid in the body increases, so does the concentration of uric acid in the joint liquid and beyond a critical concentration, the uric acid begins to precipitate into crystals.
Limit these in diet: Trans fats; Saturated fats to less than 10% of calories; Added sugars to less than 10% of calories; Sodium to less than 2.3 g/day (5.8 g of salt/day), including both added table salt and salt in foods; If consumed, use alcohol in moderation and only for adults — up to 1 drink daily for women and 2 drinks daily for men. [23]