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n/a Ensembl ENSG00000152291 n/a UniProt O43493 n/a RefSeq (mRNA) NM_006464 NM_001206840 NM_001206841 NM_001206844 NM_001368095 NM_001368096 n/a RefSeq (protein) NP_001193769 NP_001193770 NP_001193773 NP_006455 NP_001355024 NP_001355025 n/a Location (UCSC) Chr 2: 85.32 – 85.33 Mb n/a PubMed search n/a Wikidata View/Edit Human Trans-Golgi network integral membrane protein 2 is a protein that ...
68299 Ensembl ENSG00000283883 ENSG00000141252 ENSMUSG00000017288 UniProt Q5VIR6 Q8CCB4 RefSeq (mRNA) NM_001128159 NM_018289 NM_001366253 NM_001366254 NM_026664 NM_001364738 RefSeq (protein) NP_001121631 NP_060759 NP_001353182 NP_001353183 NP_080940 NP_001351667 Location (UCSC) Chr 17: 0.51 – 0.72 Mb Chr 11: 75.94 – 76.07 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Vacuolar ...
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi transmembrane protein. It processes protein synthesized in the rough endoplasmic reticulum and assists in the transport of protein cargo through the Golgi apparatus.
The PACS-1 protein has a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain.
Protein targeting or protein sorting is the biological mechanism by which proteins are transported to their appropriate destinations within or outside the cell. [ 1 ] [ 2 ] [ note 1 ] Proteins can be targeted to the inner space of an organelle , different intracellular membranes , the plasma membrane , or to the exterior of the cell via secretion .
COPI is a coatomer that coats the vesicles transporting proteins from the Golgi complex to the ER. [4] This pathway is referred to as retrograde transport. Before the COP I protein can coat vesicles on the Golgi membrane, it must interact with a small GTPase called ARF1 (ADP ribosylation factor). [5]
780776 383103 Ensembl ENSG00000166676 ENSMUSG00000050908 UniProt A6NH52 n/a RefSeq (mRNA) NM_001079512 NM_001318873 NM_001013778 NM_001359069 RefSeq (protein) NP_001072980 NP_001305802 n/a Location (UCSC) Chr 16: 10.76 – 10.82 Mb Chr 16: 10.24 – 10.27 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Trans-Golgi network vesicle protein 23 A (TVP23A) is a protein coded for the ...
The endoplasmic-reticulum–Golgi intermediate compartment (ERGIC) is an organelle in eukaryotic cells. This compartment mediates transport between the endoplasmic reticulum (ER) and Golgi complex, facilitating the sorting of cargo. [1] The cluster was first identified in 1988 using an antibody to the protein that has since been named ERGIC-53. [2]