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Although all anabolic steroids have androgenic effects, some of them paradoxically results in feminization, such as breast tissue in males, a condition called gynecomastia. These side effect are caused by the natural conversion of testosterone into estrogen and estradiol by the action of aromatase enzyme, encoded by the CYP19A1 gene. [105]
It can also cause liver damage and cardiovascular side effects like high blood pressure. [1] [7] [8] The drug is a synthetic androgen and anabolic steroid and hence is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT).
It is also used in the treatment of high blood pressure, and low blood potassium that does not improve with supplementation, early puberty in boys, acne and excessive hair growth in women. [ 4 ] [ 22 ] [ 23 ] It can also be used to block the effects of testosterone in transgender women and nonbinary people undergoing feminizing hormone ...
[3] [12] It has strong anabolic effects and weak androgenic effects, which give it a mild side effect profile and make it especially suitable for use in women and children. [3] [12] [13] NPP is a nandrolone ester and a long-lasting prodrug of nandrolone in the body. [3] NPP was first described in 1957 and was introduced for medical use in 1959. [3]
Side effects of drostanolone propionate include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire. [1] It has no risk of liver damage . [ 1 ] The drug is a synthetic androgen and anabolic steroid and hence is an agonist of the androgen receptor (AR), the biological target of androgens like ...
Common side effects include nausea, pain at the site of injection, and headache. [2] It may also cause a temporary increase in blood pressure and decrease in heart rate after each dose, and darkening of the gums, face, and breasts. [4] The medication is a peptide and acts by activating the melanocortin receptors. [1] [5]
Anabolic steroids also increase muscle mass and physical strength, and are therefore used in sports and bodybuilding to enhance strength or physique. Known side effects include harmful changes in cholesterol levels (increased low-density lipoprotein and decreased high-density lipoprotein), acne, high blood pressure, and liver damage. Some of ...
Other medications for high blood pressure and a low salt diet, e.g. DASH diet, may also be needed. [1] [4] Some people with familial hyperaldosteronism may be treated with the steroid dexamethasone. [1] Primary aldosteronism is present in about 10% of people with high blood pressure. [1] It occurs more often in women than men. [5]