Search results
Results from the WOW.Com Content Network
Piperonal can be prepared by the oxidative cleavage of isosafrole or by using a multistep sequence from catechol or 1,2-methylenedioxybenzene.Synthesis from the latter chemical is accomplished through a condensation reaction with glyoxylic acid followed by cleaving the resulting α-hydroxy acid with an oxidizing agent.
The synthesis of the 1,2,4-triazole has a wide range of biological functions. [ citation needed ] 1,2,4-triazoles have antibacterial , antifungal, antidepressant and hypoglycemic properties. 3-benzylsulfanyl derivates of the triazole also show slight to moderate antimycobacterial activity, but are considered moderately toxic.
An applied example is a synthesis of sunitinib begins by mixing 5-fluoroisatin slowly into hydrazine hydrate. [9] After 4 hours at 110 °C, the indole ring structure has been broken into (2-amino-5-fluoro-phenyl)-acetic acid hydrazide with reduction of the ketone at the 3-position.
Dehydration of primary alcohols does not work well. The reagent is soluble in common organic solvents and alcohol dehydration takes place with syn elimination through an intramolecular elimination reaction. The Burgess reagent is a carbamate and an inner salt. A general mechanism is shown below.
The Shapiro reaction or tosylhydrazone decomposition is an organic reaction in which a ketone or aldehyde is converted to an alkene through an intermediate hydrazone in the presence of 2 equivalents of organolithium reagent.
An infusion basically involves steeping fruit, spices, or any other solid food product in a liquid — in this case, alcohol — so it absorbs the flavors in the food, explains Neil Grosscup, CEO ...
A related hydrazide auxiliary is the chiral acryloylhydrazide, which reacts diastereoselectively with aldehydes. [22] Both diastereomers could be obtained with different choice of solvents (DMSO vs. mixed THF and H 2 O), suggesting that the transition structure conformation is solvent-influenced.
For premium support please call: 800-290-4726 more ways to reach us