Search results
Results from the WOW.Com Content Network
Phenethylamine is a potent agonist of the mouse, rat, and human trace amine-associated receptor 1 (TAAR1). [43] [2] β-PEA is also an odorant binding TAAR4 in mice thought to mediate predator avoidance. [44] Similarly to the case of amphetamine, phenethylamine shows enhanced locomotor stimulation, a psychostimulant-like effect, in TAAR1 ...
Substituted amphetamines are a chemical class of stimulants, entactogens, hallucinogens, and other drugs. They feature a phenethylamine core with a methyl group attached to the alpha carbon resulting in amphetamine, along with additional substitutions.
β-Methylphenethylamine (β-Me-PEA, BMPEA, or 1-amino-2-phenylpropane) is an organic compound of the phenethylamine class, and a positional isomer of the drug amphetamine, with which it shares some properties. In particular, both amphetamine and β-methylphenethylamine are human TAAR1 agonists. [2] In appearance, it is a colorless or yellowish ...
Subsequently, amphetamine was used in the treatment of narcolepsy, obesity, hay fever, orthostatic hypotension, epilepsy, Parkinson's disease, alcoholism and migraine. [12] [15] The "reinforcing" effects of substituted amphetamines were quickly discovered, and the misuse of substituted amphetamines had been noted as far back as 1936. [15]
A claim of β-methyl-phenethylamine from flowers is not supported by the reference given. [42] Ether extracts about 2-6% of the dried leaf mass. [13] Alkaloids are present in the bark [43] and leaves. [44] Others found no alkaloids. [25] Claims of amphetamines and mescaline in the tree [39] appear to be groundless
Amphetamine was discovered as a chemical in 1887 by Lazăr Edeleanu, and then as a drug in the late 1920s. It exists as two enantiomers: [note 3] levoamphetamine and dextroamphetamine. Amphetamine properly refers to a specific chemical, the racemic free base, which is equal parts of the two enantiomers in their pure amine forms. The term is ...
Phentermine, also known as α,α-dimethylphenethylamine or as α-methylamphetamine, is a substituted phenethylamine and amphetamine. [ 51 ] [ 52 ] [ 53 ] It is the derivative of amphetamine in which a second methyl group is present at the alpha carbon .
Some phenethylamines and amphetamines, particularly those with methoxy and other substitions on the phenyl ring, are potent serotonin 5-HT 2 receptor agonists, including of the serotonin 5-HT 2A receptor, and can produce psychedelic effects.