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The Nikolsky sign is dislodgement of intact superficial epidermis by a shearing force, indicating a plane of cleavage in the skin epidermal-epidermal junctions (e.g., desmosomes). The histological picture involves thinner, weaker attachments of the skin lesion itself to the normal skin – resulting in easier dislodgement.
The Asboe-Hansen sign (also known as "indirect Nikolsky sign'" [1] or "Nikolsky II sign" [1]) refers to the extension of a large blister to adjacent unblistered skin when pressure is put on the top of it.
The sloughing of skin associated with certain varieties of this condition is now referred to as Nikolsky's sign. In 1898, he became a professor at the Imperial University of Warsaw, and later established the Department of Dermatology and Venerology in Rostov at what is now Rostov State Medical University. [1]
SSSS is a clinical diagnosis. This is sometimes confirmed by isolation of S. aureus from blood, mucous membranes, or skin biopsy; however, these are often negative. Skin biopsy may show separation of the superficial layer of the epidermis (intraepidermal separation), differentiating SSSS from TEN, wherein the separation occurs at the dermo-epidermal junction (subepidermal separation).
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Nikolsky (surname), including a list of people with the name; Nikolski Air Station, an airport located in Nikolski, Alaska; Nikolskoye Airport, an airport in Kamchatka Krai, Russia; Nikolski, a novel by Canadian writer Nicolas Dickner; Nikolsky Old Believer Monastery, a monastery near Preobrazhenskoye Cemetery in Moscow, Russia
Nikolai Mikhailovich Nikolsky (Russian: Николай Михайлович Никольский; 13 November 1877 – 19 November 1959) was a Russian and Soviet religious historian, orientalist and biblical scholar.
Printable version; In other projects Wikidata item; Appearance. move to sidebar hide. Nikolsky (Russian: Никольский) is a surname. Notable people with the ...
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