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In countries where dogs commonly have the disease, more than 99% of rabies cases in humans are the direct result of dog bites. [11] In the Americas, bat bites are the most common source of rabies infections in humans, and less than 5% of cases are from dogs. [1] [11] Rodents are very rarely infected with rabies. [11]
3D still showing rabies virus structure. Rhabdoviruses have helical symmetry, so their infectious particles are approximately cylindrical in shape. They are characterized by an extremely broad host spectrum ranging from plants [citation needed] to insects [citation needed] and mammals; human-infecting viruses more commonly have icosahedral symmetry and take shapes approximating regular polyhedra.
Lyssavirus (from the Greek λύσσα lyssa "rage, fury, rabies" and the Latin vīrus) [1] [2] is a genus of RNA viruses in the family Rhabdoviridae, order Mononegavirales. Mammals, including humans, can serve as natural hosts. [3] [4] The genus Lyssavirus includes the causative agent (rabies virus) of rabies. [5]
After exposure to rabies, there is no contraindication to its use, because the untreated virus is virtually 100% fatal. [11] [13] The first rabies vaccine was introduced in 1885 and was followed by an improved version in 1908. [14] Over 29 million people worldwide receive human rabies vaccine annually. [15]
In 2008, the Global Alliance for Rabies Control changed the date to 28 September, as remembrance for the day of Louis Pasteur's death, for the routine recognition of WRD, an annual global day of awareness on September 28, spreading the message of rabies prevention to millions of people, in over 100 countries. [15]
A zoonosis (/ z oʊ ˈ ɒ n ə s ɪ s, ˌ z oʊ ə ˈ n oʊ s ɪ s / ⓘ; [1] plural zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as a bacterium, virus, parasite, or prion) that can jump from a non-human vertebrate to a human. When humans infect non-humans, it is called reverse ...
The human coronavirus NL63 shared a common ancestor with a bat coronavirus (ARCoV.2) between 1190 and 1449 CE. [76] The human coronavirus 229E shared a common ancestor with a bat coronavirus (GhanaGrp1 Bt CoV) between 1686 and 1800 CE. [77] More recently, alpaca coronavirus and human coronavirus 229E diverged sometime before 1960. [78]
A public health emergency of international concern (PHEIC / f eɪ k / FAYK) is a formal declaration by the World Health Organization (WHO) of "an extraordinary event which is determined to constitute a public health risk to other States through the international spread of disease and to potentially require a coordinated international response", formulated when a situation arises that is ...