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  2. Notochord - Wikipedia

    en.wikipedia.org/wiki/Notochord

    Persistence of notochordal cells within the vertebra may cause a pathologic condition: persistent notochordal canal. [17] If the notochord and the nasopharynx do not separate properly during embryonic development, a depression (Tornwaldt bursa) or Tornwaldt cyst may form. [18] The cells are the likely precursors to a rare cancer called chordoma ...

  3. Chordoma - Wikipedia

    en.wikipedia.org/wiki/Chordoma

    Chordoma is a rare slow-growing neoplasm thought to arise from cellular remnants of the notochord.The evidence for this is the location of the tumors (along the neuraxis), the similar immunohistochemical staining patterns, and the demonstration that notochordal cells are preferentially left behind in the clivus and sacrococcygeal regions when the remainder of the notochord regresses during ...

  4. Axial mesoderm - Wikipedia

    en.wikipedia.org/wiki/Axial_mesoderm

    Axial mesoderm, or chordamesoderm, is the mesoderm in the embryo that lies along the central axis under the neural tube.. will give rise to notochord; starts as the notochordal process, whose formation finishes at day 20 in humans.

  5. T-box transcription factor T - Wikipedia

    en.wikipedia.org/wiki/T-box_transcription_factor_T

    20997 Ensembl ENSG00000164458 ENSMUSG00000062327 UniProt O15178 P20293 RefSeq (mRNA) NM_001270484 NM_003181 NM_001366285 NM_001366286 NM_009309 RefSeq (protein) NP_001257413 NP_003172 NP_001353214 NP_001353215 NP_033335 Location (UCSC) Chr 6: 166.16 – 166.17 Mb Chr 17: 8.65 – 8.66 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse T-box transcription factor T, also known as ...

  6. Neurulation - Wikipedia

    en.wikipedia.org/wiki/Neurulation

    Prior to neurulation, during the migration of epiblastic endoderm cells towards the hypoblastic endoderm, the notochordal process opens into an arch termed the notochordal plate and attaches overlying neuroepithelium of the neural plate. The notochordal plate then serves as an anchor for the neural plate and pushes the two edges of the plate ...

  7. Neurenteric canal - Wikipedia

    en.wikipedia.org/wiki/Neurenteric_canal

    The neurenteric canal is also known as the canal of Kovalevsky. In the development of vertebrate animals, during the 6th Carnegie stage, the proximal part of the notochordal canal persists temporarily as the neurenteric canal, which forms a transitory communication between the amniotic sac and the yolk sac cavities.

  8. Convergent extension - Wikipedia

    en.wikipedia.org/wiki/Convergent_extension

    As it involutes, it converges along the mediolateral axis and extends along the future anterior-posterior axis of the notochordal and somitic mesoderm. Convergence and extension of these tissues squeezes the blastopore shut and simultaneously elongate the body axis.

  9. Neurula - Wikipedia

    en.wikipedia.org/wiki/Neurula

    Notochordal cells become arranged in a formation representing a stack of coins in a process termed circumferential intercalation. The superficial layer of the IMZ develops into the roof of the archenteron , or the primitive gut, while the underlying endoderm forms the archenteron floor.