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Descemet membrane endothelial keratoplasty (DMEK) is a method of corneal transplantation that involves the removal of a thin sheet of tissue from the posterior (innermost) side of a person's cornea to replace it with the two posterior (innermost) layers of corneal tissue from a donor's eyeball.
Szurman's area of expertise is minimally invasive eye surgery, including retinal vitrectomy, treatment of macular degeneration, corneal transplantation with laser and partial grafts (DMEK), stem cell therapy for corneal surface healing disorders after corrosive injuries and burns, trauma reconstruction, glaucoma surgery with microcatheters (canaloplasty), and laser surgery for cataracts.
Corneal transplantation, also known as corneal grafting, is a surgical procedure where a damaged or diseased cornea is replaced by donated corneal tissue (the graft). When the entire cornea is replaced it is known as penetrating keratoplasty and when only part of the cornea is replaced it is known as lamellar keratoplasty.
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Postoperative wounds are those wounds acquired during surgical procedures. Postoperative wound healing occurs after surgery and normally follows distinct bodily reactions: the inflammatory response, the proliferation of cells and tissues that initiate healing, and the final remodeling.
A week after the injury, the edges of the wound are pulled together by contraction. Contraction is an important part of the healing process when damage has been extensive, and involves shrinking in size of underlying contractile connective tissue, which brings the wound margins toward one another. [1]
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The amount of corneal hazing after surgery is also decreased with brush technique. [12] The platelet activating factor blocker LAU-0901 has shown effect in mitigating dry eye in mouse models. [ 13 ] Rabbit models have also shown improvement with topical nerve growth factor (NGF) in combination with docosahexaenoic acid (DHA). [ 14 ]