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Aortic regurgitation (AR), also known as aortic insufficiency (AI), is the leaking of the aortic valve of the heart that causes blood to flow in the reverse direction during ventricular diastole, from the aorta into the left ventricle. As a consequence, the cardiac muscle is forced to work harder than normal.
Aortic valve repair or aortic valve reconstruction is the reconstruction of both form and function of a dysfunctional aortic valve. Most frequently it is used for the treatment of aortic regurgitation. [1] It can also become necessary for the treatment of aortic aneurysm, less frequently for congenital aortic stenosis.
Medical signs of aortic regurgitation include increased pulse pressure by increased systolic and decreased diastolic blood pressure, [16] but these findings may not be significant if acute. [15] The patient may have a diastolic decrescendo murmur best heard at left sternal border, water hammer pulse , Austin Flint murmur , and a displaced apex ...
Aortic valve repair or aortic valve reconstruction describes the reconstruction of both form and function of the native and dysfunctioning aortic valve. Most frequently it is applied for the treatment of aortic regurgitation. It can also become necessary for the treatment of an aortic aneurysm, less frequently for congenital aortic stenosis. [53]
The aortic valve is opened during systole, the driving force for it to open is the difference in pressure between the contracting left ventricle of the heart and the aorta. During cardiac diastole (when the heart chamber gets bigger) the aortic valve closes. [5] Aortic stenosis most commonly is the result of calcification of the cusps.
The ALIGN-AR 2-year Follow-Up data confirmed the continued safety and efficacy of the Trilogy heart valve system for patients with severe, symptomatic aortic regurgitation (AR) at high risk for surgery. After two years, the all-cause mortality rate remained below the study's predefined performance goal of 25% at one year.
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