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Over thousands of years, in many climate zones, genetic selection has helped indigenous human populations adapt toward skin pigmentation levels that provide a healthy level of UV exposure. This largely explains the tendency toward darker-skinned populations in the sunniest tropical environments, and lighter skin tones in less-sunny regions and ...
Low levels of vitamin D3 are more commonly found in individuals living in northern latitudes or with other reasons for a lack of regular sun exposure, including being housebound, frail, elderly, or obese, having darker skin, and wearing clothes that cover most of the skin. [23] [24] Supplements are recommended for these groups of people. [24]
Vitamin K2 may have a protective effect on bone mineral density and reduced risk of hip, vertebral and non-vertebral fractures. [11] These effects appear to be accentuated when combined with vitamin D and in the setting of osteoporosis. [1] Research suggests that vitamin K 2 (Menaquinone 7, MK-7]) may reduce the rate and severity of night time ...
Vitamin D3, aka cholecalciferol, is important for bone health and immune function. Experts discuss benefits, sources, risks and who needs a supplement.
While serum low 25-hydroxyvitamin D status has been associated with a higher risk of cancer in observational studies, [101] [102] [103] the general conclusion is that there is insufficient evidence for an effect of vitamin D supplementation on the risk of cancer, [2] [104] [105] although there is some evidence for reduction in cancer mortality.
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Ergocalciferol may be used as a vitamin D supplement, whereas cholecalciferol (vitamin D 3) is produced naturally by the skin when exposed to ultraviolet light. [15] Ergocalciferol (D 2 ) and cholecalciferol (D 3 ) are considered to be equivalent for vitamin D production, as both forms appear to have similar efficacy in ameliorating rickets ...
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