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  2. Plazomicin - Wikipedia

    en.wikipedia.org/wiki/Plazomicin

    Plazomicin, sold under the brand name Zemdri, is an aminoglycoside antibiotic used to treat complicated urinary tract infections. [2] As of 2019 it is recommended only for those in whom alternatives are not an option. [2] It is given by injection into a vein. [2] Common side effects include kidney problems, diarrhea, nausea, and blood pressure ...

  3. Aminoglycoside - Wikipedia

    en.wikipedia.org/wiki/Aminoglycoside

    Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some Mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Streptomycin was the first effective drug in the treatment of tuberculosis, though ...

  4. Antibiotic synergy - Wikipedia

    en.wikipedia.org/wiki/Antibiotic_synergy

    A classic example of this effect is the interaction between β-lactams, which damage the bacteria cell membrane, and aminoglycosides, which inhibit protein synthesis. [1] The damage dealt to the cell wall by β-lactams allows more aminoglycoside molecules to be taken up into the cell than would otherwise be possible, enhancing cell damage. [1]

  5. Amikacin - Wikipedia

    en.wikipedia.org/wiki/Amikacin

    While amikacin is only FDA-approved for use in dogs and for intrauterine infection in horses, it is one of the most common aminoglycosides used in veterinary medicine, [35] and has been used in dogs, cats, guinea pigs, chinchillas, hamsters, rats, mice, prairie dogs, cattle, birds, snakes, turtles and tortoises, crocodilians, bullfrogs, and fish.

  6. List of antibiotics - Wikipedia

    en.wikipedia.org/wiki/List_of_antibiotics

    Urinary tract infections, bacterial prostatitis, community-acquired pneumonia, bacterial diarrhea, mycoplasmal infections, gonorrhea: Nausea (rare), irreversible damage to central nervous system (uncommon), tendinosis (rare) Inhibits the bacterial DNA gyrase or the topoisomerase IV enzyme, thereby inhibiting DNA replication and transcription ...

  7. Tobramycin - Wikipedia

    en.wikipedia.org/wiki/Tobramycin

    Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius that is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas. [9] It was patented in 1965, and approved for medical use in 1974. [10]

  8. Category:Aminoglycoside antibiotics - Wikipedia

    en.wikipedia.org/wiki/Category:Aminoglycoside...

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  9. Macrolide - Wikipedia

    en.wikipedia.org/wiki/Macrolide

    AUC it is a measure of the drug exposure in the body over time. By inhibiting CYP3A4, macrolide antibitiotics, such as erythromycin and clarithromycin, but not azithromycin, can significantly increase the AUC of the drugs that depend on it for clearance, which can lead to higher risk of adverse effects or drug-drug interactions. Azithromycin ...

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