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Ocrelizumab, sold under the brand name Ocrevus, is a medication used for the treatment of multiple sclerosis.It is a humanized anti-CD20 monoclonal antibody. [8] It targets CD20 marker on B lymphocytes and is an immunosuppressive drug. [10]
OhioHealth Doctors Hospital is a 213-bed tertiary care teaching hospital located in Columbus in the U.S. state of Ohio. Doctors Hospital operates the second largest osteopathic medical training program in the United States.
This may be because of lack of funding to go through the approval process. Some doctors prescribe them off-label or under the schema of open label research. Examples of MS drugs used off label include: rituximab - Monoclonal antibody against CD20. According to some sources it has a better efficacy vs. safety profile than most approved drugs. [76]
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In the United states, natalizumab is indicated for the treatment of multiple sclerosis and Crohn's disease. [1] [9] It is indicated to treat clinically isolated syndrome – a single, first occurrence of multiple sclerosis symptoms; relapsing-remitting disease – a type of multiple sclerosis that occurs when people have episodes of new neurological symptoms followed by periods of stability ...
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