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The notochord is derived from the embryonic mesoderm and consists of an inner core of vacuolated cells filled with glycoproteins, covered by two helical collagen-elastin sheaths. It lies longitudinally along the rostral-caudal (head to tail) axis of the body, dorsal to the gut tube, and ventral to the dorsal nerve cord.
A notochord, a stiff but elastic rod of glycoprotein wrapped in two collagen helices, which extends along the central axis of the body. Among members of the subphylum Vertebrata (vertebrates), the notochord gets replaced by hyaline cartilage or osseous tissue of the spine , and notochord remnants develop into the intervertebral discs , which ...
The dorsal nerve cord is an anatomical feature found in chordate animals, mainly in the subphyla Vertebrata and Cephalochordata, as well as in some hemichordates.It is one of the five embryonic features unique to all chordates, the other four being a notochord, a post-anal tail, an endostyle, and pharyngeal slits.
The chorda-mesoderm develops into the notochord. The intermediate mesoderm develops into kidneys and gonads. The paraxial mesoderm develops into cartilage, skeletal muscle, and dermis. The lateral plate mesoderm develops into the circulatory system (including the heart and spleen), the wall of the gut, and wall of the human body. [11]
This forms the notochord, which induces the formation of the neural tube, and establishes the anterior-posterior body axis. The notochord extends beneath the neural tube from the head to the tail. The mesoderm moves to the midline until it covers the notochord. When the mesoderm cells proliferate, they form the paraxial mesoderm.
Cells in this area, known as medial hinge point cells because of their involvement with this structure, are stabilized and connected to the notochord. They are derived from the area of the neural plate anterior to primitive knot. The notochord will begin the shape changes in MHP cells. These cells will decrease in height and become wedge-shaped.
Homeobox protein notochord (NOTO) is a transcription factor [1] encoded by the gene notochord homeobox (NOTO) located on the short arm of chromosome 2 (2p13.2) in humans (Homo sapiens). [2] An ortholog of NOTO is found in the house mouse ( Mus musculus ), among other species, as the gene notochord homeobox ( Noto ) located on chromosome 6 ...
The notochord was reinterpreted to run underneath the dorsal organ a thin rod-like filament. The body segments are anatomically blocks of skeletal muscles, called the myomeres, which are found in vertebrates only. No eyes can be observed. [24] The muscle orientation and flat shaped body indicate that Pikaia was an active and free swimmer. [8]