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Lymphedema is most frequently a complication of cancer treatment or parasitic infections, but it can also be seen in a number of genetic disorders. Tissues with lymphedema are at high risk of infection because the lymphatic system has been compromised. [3] Though incurable and progressive, a number of treatments may improve symptoms. [2]
Milroy's disease is also known as primary or hereditary lymphedema type 1A or early onset lymphedema. It is a very rare disease with only about 200 cases reported in the medical literature. Milroy's disease is an autosomal dominant condition caused by a mutation in the FLT4 gene which encodes the vascular endothelial growth factor receptor 3 ...
Heavy-headedness is the feeling of faintness, dizziness, or feeling of floating, wooziness. [1] [2] [3] Individuals may feel as though their head is heavy; also feel as though the room is moving/spinning also known as vertigo. Some causes of heavy-headedness can be tough to get rid of and can last a long period of time, however most can be treated.
The pathophysiology is not yet well understood. Leukocytoclastic vasculitis is proposed to be the underlying cause resulting in reactive lymphedema. [2] Prolonged standing with full knee extension and minimal movement for a prolonged period of time is postulated to induce a temporary failure in pumping the venous and lymphatic systems in the calf region leading to acute gravity-dependent ...
Treatment may include drinking plenty of water or other fluids (unless the lightheadedness is the result of water intoxication in which case drinking water is quite dangerous). If a patient is unable to keep fluids down from nausea or vomiting, they may need intravenous fluids such as Ringer's lactate solution .
Meige disease is a primary lymphedema that is not caused by another condition; secondary lymphedema is a typical consequence of a mastectomy. Another primary lymphedema is Milroy disease in which the lymphedema is present at birth. [3] Lymphedema tarda occurs after the age of 35. [4] Meige disease has its onset around the time of puberty.
Many conditions cause dizziness because multiple parts of the body are required for maintaining balance including the inner ear, eyes, muscles, skeleton, and the nervous system. [7] Thus dizziness can be caused by a variety of problems and may reflect a focal process (such as one affecting balance or coordination ) or a diffuse one (such as a ...
The most successful treatment for lymphangiosarcoma is amputation of the affected limb if possible. Chemotherapy may be administered if there is evidence or suspicion of metastatic disease. Evidence supporting the effectiveness of chemotherapy is, in many cases, unclear due to a wide variety of prognostic factors and small sample size.