Search results
Results from the WOW.Com Content Network
Toxic multinodular goiter (TMNG), also known as multinodular toxic goiter (MNTG), is an active multinodular goiter associated with hyperthyroidism.. It is a common cause of hyperthyroidism [2] [3] in which there is excess production of thyroid hormones from functionally autonomous thyroid nodules, which do not require stimulation from thyroid stimulating hormone (TSH).
They inhibit release of thyroid hormones by the thyroid gland.The most studied drug in this class is lithium, which inhibits thyroid hormone secretion by inhibiting iodotyrosine coupling, thyroidal iodide uptake, and alteration in structure of thyroglobulin, [10] a protein which acts as a substrate for the synthesis of thyroid hormones and storage of inactive forms of T3, T4 and iodine within ...
Thiamazole is a drug used to treat hyperthyroidism such as in Graves' disease, a condition that occurs when the thyroid gland begins to produce an excess of thyroid hormone. The drug may also be taken before thyroid surgery to lower thyroid hormone levels and minimize the effects of thyroid manipulation.
Propylthiouracil (PTU) is a medication used to treat hyperthyroidism. [3] This includes hyperthyroidism due to Graves' disease and toxic multinodular goiter. [3] In a thyrotoxic crisis it is generally more effective than methimazole. [3] Otherwise it is typically only used when methimazole, surgery, and radioactive iodine is not possible. [3]
In areas where iodine-deficiency is not found, the most common type of hypothyroidism is an autoimmune subtype called Hashimoto's thyroiditis, with a prevalence of 1-2%. [40] As for hyperthyroidism, Graves' disease, another autoimmune condition, is the most common type with a prevalence of 0.5% in males and 3% in females. [41]
This may be used in those with very large thyroids or when cancer is a concern. [1] In the United States hyperthyroidism affects about 1.2% of the population. [3] Worldwide, hyperthyroidism affects 2.5% of adults. [8] It occurs between two and ten times more often in women. [1] Onset is commonly between 20 and 50 years of age. [2]
Many drugs have more than one name and, therefore, the same drug may be listed more than once. Brand names and generic names are differentiated by capitalizing brand names. See also the list of the top 100 bestselling branded drugs, ranked by sales. Abbreviations are used in the list as follows: INN = International Nonproprietary Name
Carbimazole (brand names Neo-Mercazole, Anti-Thyrox, etc.) is used to treat hyperthyroidism. Carbimazole is a pro-drug as after absorption it is converted to the active form, methimazole . Methimazole prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin , hence reducing the production of the ...