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For the treatment of the withdrawal/negative affect symptom domain of cannabis use disorder, medications may work by alleviating restlessness, irritable or depressed mood, anxiety, and insomnia. [58] Bupropion, which is a norepinephrine–dopamine reuptake inhibitor, has been studied for the treatment of withdrawal with largely poor results. [58]
Smoking cessation, usually called quitting smoking or stopping smoking, is the process of discontinuing tobacco smoking. [1] Tobacco smoke contains nicotine, which is addictive and can cause dependence. [2] [3] As a result, nicotine withdrawal often makes the process of quitting difficult.
Legal cannabis (marijuana) product. Overconsumption and reliance could lead to cannabis-induced amotivational syndrome. The term amotivational syndrome was first devised to understand and explain the diminished drive and desire to work or compete among the population of youth who are frequent consumers of cannabis and has since been researched through various methodological studies with this ...
Sanofi-Aventis has also discontinued development of surinabant (SR147778), a CB 1 receptor antagonist for smoking cessation (31 October 2008). [ 35 ] Merck has stated in its press release on 2 October 2008 that they will not seek regulatory approval for taranabant (MK-0364) to treat obesity and will discontinue its Phase III clinical ...
Nicotine withdrawal is a group of symptoms that occur in the first few weeks after stopping or decreasing use of nicotine. Symptoms include intense cravings for nicotine, anger or irritability, anxiety, depression, impatience, trouble sleeping, restlessness, hunger, weight gain, and difficulty concentrating.
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Prescribed as an aid for smoking cessation, bupropion reduces the severity of craving for nicotine and withdrawal symptoms [54] [55] [56] such as depressed mood, irritability, difficulty concentrating, and increased appetite. [57] Initially, bupropion slows the weight gain that often occurs in the first weeks after quitting smoking.
Patients who wish to come off the drugs permanently should first agree with their doctor whether it is right to stop taking the medication, and, if so, the speed and duration of withdrawal from it ...