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Tumor marker Associated tumor types Alpha fetoprotein (AFP) germ cell tumor, hepatocellular carcinoma [9] CA15-3: breast cancer [10] CA27.29: breast cancer [11] CA19-9: Mainly pancreatic cancer, but also colorectal cancer and other types of gastrointestinal cancer. [12] CA-125
Other tumor markers for ovarian cancer include ... 51.3 0.2 Brenner tumor: 67.9 0.2 ... the level of alpha-fetoprotein in the blood is a useful marker of ...
The usual markers for liver disease – aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase – are often normal or only slightly elevated. FLC often does not produce alpha fetoprotein (AFP), a widely used marker for conventional hepatocellular carcinoma.
A surge in the plasma levels of human chorionic gonadotropin and alpha-fetoprotein is indicative of OGMTs. [1] Lactate dehydrogenase, alkaline phosphatase and cancer antigen 125 might potentially increase as well. [24] To visualize the location and morphology of the tumor, transvaginal ultrasonography is usually employed. [1]
Mean platelet volume (MPV) 7.2, [147] 7.4, [148] 7.5 [149] 10.4, [148] 11.5, [149] 11.7 [147] fL: Prothrombin time (PT) 10, [18] 11, [14] [150] 12 [15] 13, [18] 13.5, [150] 14, [15] 15 [14] s: PT reference varies between laboratory kits – INR is standardised INR: 0.9 [5] 1.2 [5] The INR is a corrected ratio of a patient's PT to normal ...
The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ability to bind tumor necrosis factors (TNFs) via an extracellular cysteine-rich domain. [2] [3] With the exception of nerve growth factor (NGF), all TNFs are homologous to the archetypal TNF-alpha. [4]
Incomplete membrane staining that is faint or barely perceptible and within >10% of the invasive tumor cells. [45] 2+ Weak to moderate complete membrane staining observed in >10% of tumor cells. [45] Borderline/Equivocal 3+ Circumferential membrane staining that is complete, intense, and in >10% of tumor cells. [45] HER2 positive
Yolk sac tumor Alpha-fetoprotein is normally elevated in greater than 90% of patients with yolk sac tumor (Woodward et al., 2002, as cited in Ulbright et al., 1999). In its pure form, yolk sac tumor is rare in adults; however yolk sac elements are frequently seen in tumors with mixed histologic features in adults and thus indicate poor prognosis.
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