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  2. Positive and negative predictive values - Wikipedia

    en.wikipedia.org/wiki/Positive_and_negative...

    The positive predictive value (PPV), or precision, is defined as = + = where a "true positive" is the event that the test makes a positive prediction, and the subject has a positive result under the gold standard, and a "false positive" is the event that the test makes a positive prediction, and the subject has a negative result under the gold standard.

  3. Predictive value of tests - Wikipedia

    en.wikipedia.org/wiki/Predictive_value_of_tests

    Predictive value of tests is the probability of a target condition given by the result of a test, [1] often in regard to medical tests.. In cases where binary classification can be applied to the test results, such yes versus no, test target (such as a substance, symptom or sign) being present versus absent, or either a positive or negative test), then each of the two outcomes has a separate ...

  4. Pre- and post-test probability - Wikipedia

    en.wikipedia.org/wiki/Pre-_and_post-test_probability

    Also, in this case, the positive post-test probability (the probability of having the target condition if the test falls out positive), is numerically equal to the positive predictive value, and the negative post-test probability (the probability of having the target condition if the test falls out negative) is numerically complementary to the ...

  5. Cell-free fetal DNA - Wikipedia

    en.wikipedia.org/wiki/Cell-free_fetal_DNA

    The sequencing gave sensitivity of 100 percent, specificity of 97.9 percent, a positive predictive value of 96.6 percent and a negative predictive value of 100 percent. [ citation needed ] Mass spectrometry

  6. False positives and false negatives - Wikipedia

    en.wikipedia.org/wiki/False_positives_and_false...

    The false positive rate (FPR) is the proportion of all negatives that still yield positive test outcomes, i.e., the conditional probability of a positive test result given an event that was not present. The false positive rate is equal to the significance level. The specificity of the test is equal to 1 minus the false positive rate.

  7. Aneuploidy - Wikipedia

    en.wikipedia.org/wiki/Aneuploidy

    Aneuploidy originates during cell division when the chromosomes do not separate properly between the two cells (nondisjunction). Most cases of aneuploidy in the autosomes result in miscarriage, and the most common extra autosomal chromosomes among live births are 21, 18 and 13. [5] Chromosome abnormalities are detected in 1 of 160 live human ...

  8. Likelihood ratios in diagnostic testing - Wikipedia

    en.wikipedia.org/wiki/Likelihood_ratios_in...

    In fact, post-test probability, as estimated from the likelihood ratio and pre-test probability, is generally more accurate than if estimated from the positive predictive value of the test, if the tested individual has a different pre-test probability than what is the prevalence of that condition in the population.

  9. Prenatal testing - Wikipedia

    en.wikipedia.org/wiki/Prenatal_testing

    Meanwhile, of the 3792 women told they are low-risk by the Quad test, 2 of them will go on to deliver a baby with Down syndrome. The Quad test is therefore said to have a 4% positive predictive value (PPV) because only 4% of women who are told they are "high-risk" by the screening test actually have an affected fetus. The other 96% of the women ...