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However, some medications can help the heart to pump more effectively and reduce the symptoms of congestive heart failure. Common treatments for DCM in dogs include: 1.
Enalapril, sold under the brand name Vasotec among others, is an ACE inhibitor medication used to treat high blood pressure, diabetic kidney disease, and heart failure. [5] For heart failure, it is generally used with a diuretic, such as furosemide. [6] It is given by mouth or by injection into a vein. [5]
Pimobendan is indicated for the management of the signs of mild, moderate, or severe congestive heart failure in dogs due to clinical myxomatous mitral valve disease (MMVD) or dilated cardiomyopathy (DCM); [1] [7] and for use with concurrent therapy for congestive heart failure (e.g.,furosemide, etc.) as appropriate on a case-by-case basis. [1]
Enalaprilat is the active metabolite of enalapril. It is the first dicarboxylate-containing ACE inhibitor and was developed partly to overcome these limitations of captopril. The thiol functional group of captopril was replaced with a carboxylic acid group, but additional modifications were required to achieve a potency similar to captopril.
Dilated cardiomyopathy (DCM) is a condition in which the heart becomes enlarged and cannot pump blood effectively. [3] Symptoms vary from none to feeling tired, leg swelling, and shortness of breath. [2] It may also result in chest pain or fainting. [2] Complications can include heart failure, heart valve disease, or an irregular heartbeat. [3] [4]
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Boxer cardiomyopathy (also known as "Boxer arrhythmogenic right ventricular cardiomyopathy") is a disease of the myocardium primarily affecting Boxer dogs.It is characterized by the development of ventricular tachyarrhythmias, resulting in syncope and sudden cardiac death.
Puppies and adult dogs diagnosed with subaortic stenosis can suffer from a range of clinical signs such as fainting, breathing difficulty in the moderate cases or heart failure and sudden death in severe cases. [2] Symptoms also include sudden/strong lethargicism, continuous heavy panting, and a rise in temperature.
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