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Administration of high-dose testosterone in men over a course of weeks can cause an increase in aggression and hypomanic symptoms, though these were seen in only a minority of subjects. [15] Acute high-dose anabolic-androgenic steroid administration in males attenuates endogenous sex hormone production and affects the thyroid hormone axis.
To prevent steroid-induced osteoporosis, the steroid dose and duration should be as low and as short as possible. All patients on long term glucocorticoids (≥3 months) should be encouraged to do weightbearing exercise, avoid smoking and excess alcohol and take fall prevention measures. Daily calcium and vitamin d intake should be sufficient.
Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [4] [5] [6] It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares.
[8] [15] Nandrolone has strong anabolic effects and weak androgenic effects, which give them a mild side effect profile and make them especially suitable for use in women and children. [ 8 ] [ 15 ] [ 16 ] There are metabolites of Nandrolone that act as long-lasting prodrugs in the body, [ 8 ] such as 5α-Dihydronandrolone .
The high doses of testosterone required to increase sexual desire in women may have a significant risk of masculinization with long-term therapy. [41] [40] For this reason, and due to the unknown health effects and safety of testosterone therapy, its use may be inappropriate.
[52] [49] [53] [54] Nonetheless, it is useful as an antiandrogen in women, who have low androgen levels compared to men. [55] [56] In addition, instances of gynecomastia, decreased libido, and erectile dysfunction have been reported in men taking very high doses of spironolactone (200 to 400 mg/day). [55]
13 other side gigs to make money as a retiree. While the top jobs in our list are well supported by BLS data for those over 55, you might be looking to break from the nine-to-five altogether for ...
Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol under the brand names Diane or Diane-35 among others, is an antiandrogen and progestin medication used in the treatment of androgen-dependent conditions such as acne, excessive body hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender individuals ...