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Sir Frederick Grant Banting (November 14, 1891 – February 21, 1941) was a Canadian pharmacologist, orthopedist, and field surgeon. [3] For his co-discovery of insulin and its therapeutic potential, Banting was awarded the Nobel Prize in Physiology or Medicine with John Macleod.
Douglas Grundy/Three Lions via Getty ImagesDiabetes was a fatal disease before insulin was discovered on July 27, 1921. A century ago, people diagnosed with this metabolic disorder usually ...
Nicolae Constantin Paulescu (Romanian pronunciation: [nikoˈla.e pa.uˈlesku]; 30 October 1869 (O.S.) – 17 July 1931) was a Romanian physiologist, professor of medicine, and politician, most famous for his work on diabetes, including patenting pancreine (a pancreatic extract containing insulin).
John Macleod was a distinguished physiologist even before the discovery of insulin. He was elected a member of the Royal Society of Canada in 1919 and president of American Physiological Society in 1921. [19] In 1923, Macleod was awarded the Cameron Prize for Therapeutics of the University of Edinburgh.
"It was an accident" is never a phrase that you want to hear in the laboratory -- well, almost never. After all, taking an experimental drug from the fume hood of a chemistry lab all the way to ...
Insulin is a peptide hormone containing two chains cross-linked by disulfide bridges. Insulin (/ ˈ ɪ n. sj ʊ. l ɪ n /, [5] [6] from Latin insula, 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the insulin (INS) gene. It is the main anabolic hormone of the body. [7]
James Bertram Collip (November 20, 1892 – June 19, 1965) was a Canadian biochemist who was part of the Toronto group which isolated insulin.He served as the chair of the department of biochemistry at McGill University from 1928 to 1941 and dean of medicine at the University of Western Ontario from 1947 to 1961, where he was a charter member of The Kappa Alpha Society.
The determination of the amino acid sequence of insulin (by Sir Frederick Sanger, for which he received a Nobel Prize). Insulin was the first protein that the amino acid structure was determined. [147] The radioimmunoassay for insulin, as discovered by Rosalyn Yalow and Solomon Berson (gaining Yalow the 1977 Nobel Prize in Physiology or ...