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In parallel to albuminuria in 1936, discussion on renal lesions observed in patients with diabetes led to the description, by Kimmelstiel and Wilson, of the characteristic nodular fibrotic observed in the diabetic glomeruli (Kimmelstiel and Wilson, 1936b). Kimmelstiel and Wilson introduced the term diabetic nephropathy (DN) to define a clinical ...
Diabetic nephropathy is the most common cause of end-stage renal disease and is a serious complication that affects approximately one quarter of adults with diabetes in the United States. [ 13 ] [ 14 ] Affected individuals with end-stage kidney disease often require hemodialysis and eventually kidney transplantation to replace the failed kidney ...
Mees' lines can look similar to injury to the nail, which should not be confused with true Mees' lines. [1]Mees' lines appear after an episode of poisoning with arsenic, [2] thallium or other heavy metals or selenium, [3] opioid MT-45, and can also appear if the subject is suffering from kidney failure. [4]
Why Wilson's disease causes hemolysis is unclear, but various lines of evidence suggest that a high level of free (nonceruloplasmin-bound) copper may be directly affecting the oxidation of hemoglobin, or inhibiting the energy-supplying enzymes in red blood cells, or causing direct damage to cell membranes.
Knuckle pads are benign subcutaneous fibrotic nodules that are seen in the finger joints and/or the extensor area of the foot. [6] [7] [8] From a clinical perspective, these are well-defined, non-compressible, freely moveable lesions that resemble warts and primarily affect the dorsal portion of the proximal interphalangeal (PIP) and, less frequently, the metacarpophalangeal (MCP) joints.
There are several causes of Beau's lines. It is believed that there is a temporary cessation of cell division in the nail matrix.This may be caused by an infection or problem in the nail fold, where the nail begins to form, or it may be caused by an injury to that area.
The post Look: Russell Wilson Suffers Gruesome Finger Injury appeared first on The Spun. On Thursday night, the Seattle Seahawks and Los Angeles Rams met in a highly-anticipated NFC showdown. It ...
Certain drugs (for example, amlodipine) can cause pedal edema. Cerebral edema is extracellular fluid accumulation in the brain. [1] It can occur in toxic or abnormal metabolic states and conditions such as systemic lupus or reduced oxygen at high altitudes. It causes drowsiness or loss of consciousness, leading to brain herniation and death.