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What is a GLP-1 medication? GLP-1 medications are drugs that mimic the effects of the GLP-1 hormone, helping regulate blood sugar and reduce appetite. They are primarily used for managing type 2 ...
Researchers recently conducted a review to examine what effects GLP-1 medications may have on cognitive functioning and mental health issues. The scientists found mixed results: While some studies ...
A previous review of 28 randomized control trials showed that GLP-1s lowered the incidence of respiratory diseases. ... As the GLP-1 patients in Al-Aly’s study were all veterans, with full drug ...
The initial product GLP-1 (1–37) is susceptible to amidation and proteolytic cleavage, which gives rise to the two truncated and equipotent biologically active forms, GLP-1 (7–36) amide and GLP-1 (7–37). Active GLP-1 protein secondary structure includes two α-helices from amino acid position 13–20 and 24–35 separated by a linker region.
Native GLP-1 is a peptide hormone with a half-life of two minutes because it is rapidly cleared by the enzyme dipeptidyl peptidase-4. [29] As a result, different GLP-1 agonist drugs are modified in various ways to extend the half-life, resulting in drugs that can be dosed multiple times per day, daily, weekly, or less often. [29]
Most people know that GLP-1 receptor agonist medications like Ozempic and Wegovy can cause relatively minor side effects like nausea and diarrhea. But new research confirms that more serious ...
A new study compares the benefits and risks of taking GLP-1 medications for weight loss, including risks of dementia, addiction, heart disease, and gastrointestinal problems, among others.
Beyond being a GLP-1 receptor agonist, tirzepatide is an insulinotropic polypeptide (GIP) receptor agonist. ... medical evaluation, and review of your personal medical history.