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Tubular secretion occurs simultaneously during re-absorption of filtrate. Substances, generally produced by body or the by-products of cell metabolism that can become toxic in high concentration, and some drugs (if taken). These all are secreted into the lumen of renal tubule. Tubular secretion can be either active or passive or co-transport.
The proximal tubule is the segment of the nephron in kidneys which begins from the renal pole of the Bowman's capsule to the beginning of loop of Henle.At this location, the glomerular parietal epithelial cells (PECs) lining bowman’s capsule abruptly transition to proximal tubule epithelial cells (PTECs).
The collecting duct system of the kidney consists of a series of tubules and ducts that physically connect nephrons to a minor calyx or directly to the renal pelvis.The collecting duct participates in electrolyte and fluid balance through reabsorption and excretion, processes regulated by the hormones aldosterone and vasopressin (antidiuretic hormone).
The renal corpuscle is the site of the filtration of blood plasma. The renal corpuscle consists of the glomerulus, and the glomerular capsule or Bowman's capsule. [4]: 1027 The renal corpuscle has two poles: a vascular pole and a tubular pole.
The processes of blood plasma filtration, tubular reabsorption and tubular secretion occur in the kidneys, and urine formation is a result of these processes. [8] The kidneys produce renin [32] and erythropoietin [33] hormones, and are involved in the conversion of vitamin D to its active form. [34]
Renal corpuscle showing glomerulus and glomerular capillaries Figure 2: (a) Diagram of the juxtaglomerular apparatus: it has specialized cells working as a unit which monitor the sodiujuxtaglomerular apparatus: it has three types of specm content of the fluid in the distal convoluted tubule (not labelled - it is the tubule on the left) and adjust the glomerular filtration rate and the rate of ...
The DCT is lined with simple cuboidal cells, the distal convoluted tubule cells, that are shorter than those of the proximal convoluted tubule (PCT). The lumen appears larger in the PCT than the DCT lumen because the PCT has a brush border (microvilli).
Within the nephron of the kidney, the ascending limb of the loop of Henle is a segment of the heterogenous loop of Henle downstream of the descending limb, after the sharp bend of the loop. This part of the renal tubule is divided into a thin and thick ascending limb ; the thick portion is also known as the distal straight tubule , in contrast ...