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  2. Indole-3-carbaldehyde - Wikipedia

    en.wikipedia.org/wiki/Indole-3-carbaldehyde

    Indole-3-carbaldehyde (I3A), also known as indole-3-aldehyde and 3-formylindole, is a metabolite of dietary L-tryptophan which is synthesized by human gastrointestinal bacteria, particularly species of the Lactobacillus genus.

  3. Indoleacetate decarboxylase - Wikipedia

    en.wikipedia.org/wiki/Indoleacetate_decarboxylase

    The first one consists of the degradation of the amino acid into indole-3-acetate. And in the second step, IAD catalyzes the decarboxylation of the indole-3-acetate to form the final product, skatole. The decarboxylation of indole-3-acetate is chemically difficult since it leaves an unstable carbanion because of the direct elimination of CO 2.

  4. Indole - Wikipedia

    en.wikipedia.org/wiki/Indole

    Indole is an organic compound with the formula C 6 H 4 CCNH 3. Indole is classified as an aromatic heterocycle. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered pyrrole ring. Indoles are derivatives of indole where one or more of the hydrogen atoms have been replaced by substituent groups.

  5. Biological activity - Wikipedia

    en.wikipedia.org/wiki/Biological_activity

    In pharmacology, biological activity or pharmacological activity describes the beneficial or adverse effects of a drug on living matter. [1] [2] When a drug is a complex chemical mixture, this activity is exerted by the substance's active ingredient or pharmacophore but can be modified by the other constituents. Among the various properties of ...

  6. Indolepyruvate decarboxylase - Wikipedia

    en.wikipedia.org/wiki/Indolepyruvate_decarboxylase

    The enzyme indolepyruvate decarboxylase (EC 4.1.1.74) catalyzes the chemical reaction 3-(indol-3-yl)pyruvate ⇌ {\displaystyle \rightleftharpoons } 2-(indol-3-yl)acetaldehyde + CO 2 This enzyme belongs to the family of lyases , specifically the carboxy-lyases, which cleave carbon-carbon bonds.

  7. β-Carboline - Wikipedia

    en.wikipedia.org/wiki/Β-Carboline

    β-Carboline (9H-pyrido[3,4-b]indole) represents the basic chemical structure for more than one hundred alkaloids and synthetic compounds. The effects of these substances depend on their respective substituent. Natural β-carbolines primarily influence brain functions but can also exhibit antioxidant [1] effects.

  8. Indole-3-carboxylate decarboxylase - Wikipedia

    en.wikipedia.org/wiki/Indole-3-carboxylate_de...

    Indole-3-carboxylate decarboxylase (EC 4.1.1.92) is an enzyme with systematic name indole-3-carboxylate carboxy-lyase. [1] This enzyme catalyses the following chemical reaction. indole-3-carboxylate indole + CO 2. This enzyme is activated by Zn 2+, Mn 2+ or Mg 2+.

  9. Indole-3-acetaldehyde - Wikipedia

    en.wikipedia.org/wiki/Indole-3-acetaldehyde

    Indole-3-acetaldehyde is a substrate for retina-specific copper amine oxidase, aldehyde dehydrogenase X (mitochondrial), amine oxidase B, amiloride-sensitive amine oxidase, aldehyde dehydrogenase (mitochondrial), fatty aldehyde dehydrogenase, 4-trimethylaminobutyraldehyde dehydrogenase, aldehyde dehydrogenase (dimeric NADP-preferring), aldehyde ...

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