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Diagnosis in young healthy women can be based on symptoms alone. [4] In those with vague symptoms, diagnosis can be difficult because bacteria may be present without there being an infection. [14] In complicated cases or if treatment fails, a urine culture may be useful. [3]
Bacteriuria accompanied by symptoms is a urinary tract infection while that without is known as asymptomatic bacteriuria. [1] [2] Diagnosis is by urinalysis or urine culture. [3] Escherichia coli is the most common bacterium found. [1] People without symptoms should generally not be tested for the condition. [3] Differential diagnosis include ...
Pyuria is the condition of urine containing white blood cells or pus. Defined as the presence of 6-10 or more neutrophils per high power field of unspun, voided mid-stream urine, it can be a sign of a bacterial urinary tract infection. Pyuria may be present in people with sepsis, or in older people with pneumonia.
Urethral syndrome is defined as symptoms suggestive of a lower urinary tract infection but in the absence of significant bacteriuria with a conventional pathogen. [1] It is a diagnosis of exclusion in patients with dysuria and frequency without demonstrable infection. [2] In women, vaginitis should also be ruled out. [3]
This constellation of symptoms contrasts with the classical presentation of nephrotic syndrome (excessive proteinuria >3.5 g/day, low plasma albumin levels (hypoalbuminemia) <3 g/L, generalized edema, and hyperlipidemia). [8] [10] Signs and symptoms that are consistent with nephritic syndrome include: Hematuria (red blood cells in the urine) [11]
Large studies of patients have also failed to show any correlation between lower urinary tract symptoms and a specific diagnosis. [11] Also, recently a report of lower urinary tract symptoms even with malignant features in the prostate failed to be associated with prostate cancer after further laboratory investigation of the biopsy. [10]
Diagnosis is made by history and examination. [citation needed] In immunocompromised patients, pus is present in the urine but often no organism can be cultured. In children, polymerase chain reaction sequencing of urine can detect fragments of the infectious agent. [citation needed] The procedure differs somewhat for women and men.
Diagnosis is typically based on symptoms and supported by urinalysis. [2] If there is no improvement with treatment, medical imaging may be recommended. [2] Pyelonephritis may be preventable by urination after sex and drinking sufficient fluids. [1] Once present it is generally treated with antibiotics, such as ciprofloxacin or ceftriaxone.