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David Andrew Sinclair AO (born June 26, 1969) is an Australian-American biologist and academic known for his research on aging and epigenetics. Sinclair is a professor of genetics at Harvard Medical School and the founding director of the Paul F. Glenn Laboratories for the Biological Mechanisms of Aging at Harvard.
Sirtris Pharmaceuticals, Inc. was a biotechnology company based in Cambridge, MA that developed therapies for type 2 diabetes, cancer, and other diseases. Conceived in 2004 by Harvard University biologist David Sinclair and Andrew Perlman, [1] and founded that year by Sinclair and Perlman, along with Christoph Westphal, Richard Aldrich, Richard Pops, and Paul Schimmel, [2] the company was ...
STACs have been discovered by Konrad Howitz of Biomol Inc and biologist David Sinclair. In September 2003, Howitz and Sinclair et al. published a highly cited paper reporting that polyphenols such as resveratrol [ 2 ] activate human SIRT1 and extend the lifespan of budding yeast (Howitz et al., Nature, 2003).
[53] [57] [58] [59] In 2004, Harvard University professor David Sinclair co-founded Sirtris Pharmaceuticals, the initial product of which was a resveratrol formulation. [60] [61] [62] Sirtris was purchased and made a subsidiary of GlaxoSmithKline in 2008 for $720 million and shut down in 2013, without successful drug development. [63] [64]
In 2004, he co-founded Sirtris Pharmaceuticals as CEO with Harvard biologist David Sinclair, serial entrepreneur Andrew Perlman, Richard Aldrich, Richard Pops, and Paul Schimmel. [19] [20] The company focused on resveratrol formulations and derivatives as activators of the SIRT1 enzyme.
The study, published in the Journal of Child Psychology and Psychiatry, attributed an estimated 151 million cases of psychiatric disorders over the past 75 years to leaded gas exposure in American ...
David Land / Collector: @MAGENTAMODERN. Ceramic Christmas Trees. First gracing tabletops in the 1940s, ceramic Christmas trees were a mainstay in many of our parents’ and grandparents’ homes.
Silicon Valley venture capitalists who donated hundreds of millions to Trump are bracing for a sea change in tech. "I think there's going to be a renaissance of innovation in America and we're ...
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