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Myosin X, also known as MYO10, is a protein that in humans is encoded by the MYO10 gene. [5] [6] [7] [8]Myo10 is an actin-based motor protein that can localize to the tips of the finger-like cellular protrusions known as filopodia.
Cardiac sarcomere structure featuring myosin. Myosin II (also known as conventional myosin) is the myosin type responsible for producing muscle contraction in muscle cells in most animal cell types. It is also found in non-muscle cells in contractile bundles called stress fibers. [18]
Smooth muscle tissue is mostly made of actin and myosin, [3] two proteins that interact together to produce muscle contraction and relaxation. Myosin II, also known as conventional myosin, has two heavy chains that consist of the head and tail domains and four light chains (two per head) that bind to the heavy chains in the “neck” region.
Myosin-9 also known as myosin, heavy chain 9, non-muscle or non-muscle myosin heavy chain IIa (NMMHC-IIA) is a protein which in humans is encoded by the MYH9 gene. [5] [6]Non-muscle myosin IIA (NM IIA) is expressed in most cells and tissues where it participates in a variety of processes requiring contractile force, such as cytokinesis, cell migration, polarization and adhesion, maintenance of ...
The myosin head is the part of the thick myofilament made up of myosin that acts in muscle contraction, by sliding over thin myofilaments of actin.Myosin is the major component of the thick filaments and most myosin molecules are composed of a head, neck, and tail domain; the myosin head binds to thin filamentous actin, and uses ATP hydrolysis to generate force and "walk" along the thin filament.
Myosin-1, also known as 'striated muscle myosin heavy chain 1', is a protein that in humans is encoded by the MYH1 gene. [5] [6] This gene is most highly expressed in fast type IIX/D muscle fibres of vertebrates and encodes a protein found uniquely in striated muscle; it is a class II myosin with a long coiled coil tail that dimerizes and should not be confused with 'Myosin 1' encoded by the ...
Myosin-10 also known as myosin heavy chain 10 or non-muscle myosin IIB (NM-IIB) is a protein that in humans is encoded by the MYH10 gene. [5] [6] Non-muscle myosins are expressed in a wide variety of tissues, but NM-IIB is the only non-muscle myosin II isoform expressed in cardiac muscle, where it localizes to adherens junctions within intercalated discs.
17882 Ensembl ENSG00000125414 ENSMUSG00000033196 UniProt Q9UKX2 G3UW82 RefSeq (mRNA) NM_017534 NM_001100112 NM_001039545 NM_144961 RefSeq (protein) NP_001093582 NP_060004 NP_001034634 Location (UCSC) Chr 17: 10.52 – 10.55 Mb Chr 11: 67.06 – 67.09 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Myosin-2 (myosin heavy chain 2) is a protein that in humans is encoded by the MYH2 gene ...