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The most common side effects include sleepiness, dizziness, trouble breathing, and abdominal pain. [4] Other severe side effects may include liver problems, confusion, addiction, and allergic reactions. [4] Frequent use may result in medication overuse headache. [8] Barbiturate withdrawal may occur if rapidly stopped following long term use. [9]
These side effects may occur in as many as 90% of men treated with bicalutamide monotherapy, [29] but gynecomastia is generally reported to occur in 70 to 80% of patients. [30] In the EPC trial, at a median follow-up of 7.4 years, breast pain and gynecomastia respectively occurred in 73.6% and 68.8% of men treated with 150 mg/day bicalutamide ...
Possible side effects of nicotine [2] [3] The World Health Organization and other health organisations characterise the probability of experiencing side effects as: [4] [5] Very common, ≥ 1 ⁄ 10; Common (frequent), 1 ⁄ 10 to 1 ⁄ 100; Uncommon (infrequent), 1 ⁄ 100 to 1 ⁄ 1000; Rare, 1 ⁄ 1000 to 1 ⁄ 10000; Very rare, < 1 ⁄ 10000
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The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
Potential side effects include angioedema, nephrotoxicity, and low blood pressure. [10] It was approved for medical use in the United States and in the European Union in 2015, [11] [12] [13] [7] and in Australia in 2016. [1] In 2022, it was the 165th most commonly prescribed medication in the United States, with more than 3 million prescriptions.
Adverse effects, like therapeutic effects of drugs, are a function of dosage or drug levels at the target organs, so they may be avoided or decreased by means of careful and precise pharmacokinetics, the change of drug levels in the organism in function of time after administration. Adverse effects may also be caused by drug interaction. This ...
Alfacalcidol (or 1-hydroxycholecalciferol) is an analogue of vitamin D used for supplementation in humans and as a poultry feed additive.. Alfacalcidol has a weaker impact on calcium metabolism [3] and parathyroid hormone levels [4] than calcitriol; but significant effects on the immune system, including regulatory T cells. [5]