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These growth factors modulate the differentiation of progenitor cells into osteoprogenitor cells, which are responsible for bone and cartilage formation. As a result of the demineralization process, DBM is more biologically active than undemineralized bone grafts; conversely the mechanical properties are significantly diminished. [citation needed]
The result is mineral formation not strongly controlled by the cellular processes of the animal host (i.e., remote mineralization); this may lead to unusual crystal morphologies. [ 10 ] Biologically influenced mineralization takes place when chemical conditions surrounding the site of mineral formation are influenced by abiotic processes (e.g ...
Demineralization is the opposite process of mineralization; it is a process of reduction in the mineral content in tissue or an organism. Examples include bone demineralization or tooth demineralization. Demineralization can lead to serious diseases such as osteoporosis, rickets, or tooth decay. [1]
As a result of demineralization, the bones become less rigid. Physical signs include deformities like triradiate pelvis [14] and lordosis. The patient has a typical "waddling" gait. However, these physical signs may derive from a previous osteomalacial state, since bones do not regain their original shape after they become deformed.
Mineralization may refer to: Biomineralization (mineralization in biology), when an inorganic substance precipitates in an organic matrix Mineralized tissues are tissues that have undergone mineralization, including bones, teeth, antlers, and marine shells Bone remodeling, involving demineralization and remineralization in bones
Fractures and corrective osteotomies (bone cutting) can heal, but healing may be delayed and require prolonged casting or stabilization with orthopedic hardware. A load-sharing intramedullary nail or rod is the best surgical treatment for complete fractures, symptomatic pseudofractures, and progressive asymptomatic pseudofractures in adult ...
Bone tissue is removed by osteoclasts, and then new bone tissue is formed by osteoblasts. Both processes utilize cytokine (TGF-β, IGF) signalling.In osteology, bone remodeling or bone metabolism is a lifelong process where mature bone tissue is removed from the skeleton (a process called bone resorption) and new bone tissue is formed (a process called ossification or new bone formation).
Demineralisation or demineralization may refer to: Demineralization (physiology) Bone demineralisation leading to osteoporosis; see Bone mineralization; Tooth demineralisation that leads to dental caries; see Remineralisation of teeth; Demineralizing (silk worm cocoon)