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A sequestrum (plural: sequestra) is a piece of dead bone [1] that has become separated during the process of necrosis from normal or sound bone. It is a complication (sequela) of osteomyelitis. The pathological process is as follows: infection in the bone leads to an increase in intramedullary pressure due to inflammatory exudates
Thermal effects (extremely high or low temperature) can often result in necrosis due to the disruption of cells, especially in bone cells. [16] Necrosis can also result from chemical trauma, with alkaline and acidic compounds causing liquefactive and coagulative necrosis, respectively, in affected tissues. The severity of such cases varies ...
Overview of signal transduction pathways involved in apoptosis. Cell death is the event of a biological cell ceasing to carry out its functions. This may be the result of the natural process of old cells dying and being replaced by new ones, as in programmed cell death, or may result from factors such as diseases, localized injury, or the death of the organism of which the cells are part.
Avascular necrosis (AVN), also called osteonecrosis or bone infarction, is death of bone tissue due to interruption of the blood supply. [1] Early on, there may be no symptoms. [1] Gradually joint pain may develop, which may limit the person's ability to move. [1] Complications may include collapse of the bone or nearby joint surface. [1]
However, in the process of bone formation, osteoblasts function in groups of connected cells. Individual cells cannot make bone. A group of organized osteoblasts together with the bone made by a unit of cells is usually called the osteon. Osteoblasts are specialized, terminally differentiated products of mesenchymal stem cells. [1]
Specifically, the hip bone is dissected into three segments which are the sacroiliac segment, ischiopubic segment and acetabular segment. [12] Any changes in the shape of the sciatic notch of the sacroiliac segment indicate the sex and the sexual maturation of the skeleton. [12] Females have a larger sciatic notch. [13]
A bone is a rigid organ [1] that constitutes part of the skeleton in most vertebrate animals. Bones protect the various other organs of the body, produce red and white blood cells, store minerals, provide structure and support for the body, and enable mobility.
Bones are commonly described with the terms head, neck, shaft, body and base. The head of a bone usually refers to the distal end of the bone. The shaft refers to the elongated sections of long bone, and the neck the segment between the head and shaft (or body). The end of the long bone opposite to the head is known as the base.